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cellular blue nevus A large, acquired blue nevus in which melanocytes are often clear and large, alternating with pigmented spindle cells and which may expand deeply into the subcutis; malignant change is very rare.
(05 Mar 2000)
rhodanile blue A dye mixture, considered by some to be a salt of rhodamine B and Nile blue, used to stain keratinised epithelium (red) and fibroblasts (blue), as well as spermatozoa and normal and pathologic acidophilic, basophilic, and certain neutrophilic elements of cells and tissues; used as a substitute for haematoxylin and eosin.
(05 Mar 2000)
methyl blue A sulfonated triphenylrosaniline dye used as a stain for cytoplasm, collagen, and Negri bodies, and as an antiseptic.
(05 Mar 2000)
methylene blue <chemical> Methylthionine chloride; dark green crystals or crystalline powder having a bronze-like luster, readily reduced to colourless leukomethylene blue, which in turn is readily oxidised to methylene blue. Used as a bacteriologic stain and as an indicator, and administered orally or intravenously in the treatment of congenital methemoglobinaemia and cyanide poisoning.
Pharmacological action: anti-infective agents, urinary, antidotes, dyes.
Chemical name: Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride
(12 Dec 1998)
Coomassie blue Stain commonly used non-specifically for proteins on gels. Recently renamed Kenacid Blue.
(18 Nov 1997)
Coomassie brilliant blue R-250 A general protein stain used in electrophoresis because of its unusual sensitivity.
Origin: originally, a proprietary name of Imperial Chemical; Coomassie (Kumasi), Ghana
(05 Mar 2000)
polychrome methylene blue An alkaline solution of methylene blue which undergoes progressive oxidative demethylation with aging (ripening) to produce a mixture of methylene blue, azures, and methylene violet; boiling with sodium carbonate or other oxidizing agents accomplishes this result quickly, although it is not as highly regarded.
(05 Mar 2000)
cresyl blue C17H20N3OCl; Aminodimethylaminoethyldiphenazonium chloride;a basic oxazin dye used for staining the reticulum in young erythrocytes (reticulocytes); also used in vital staining and as a selective stain for gastric surface epithelial mucin and other acid mucopolysaccharides.
(05 Mar 2000)
sea-blue histiocyte A histiocyte containing cytoplasmic granules that stain bright blue with haematologic stains such as Wright-Giemsa; found in bone marrow and in the spleen, associated with hepatosplenomegaly and thrombocytopenic purpura and in other blood diseases.
(05 Mar 2000)
sea-blue histiocyte disease Splenomegaly and mild thrombocytopenia, with histiocytes in the bone marrow which contain cytoplasmic granules that stain bright blue; sometimes familial; perhaps a lipidosis; autosomal recessive inheritance.
(05 Mar 2000)
sea-blue histiocyte syndrome <syndrome> Rare disorder consisting of splenomegaly, mild purpura secondary to thrombocytopenia, and occasionally, hepatic cirrhosis associated with the appearance of numerous histiocytes in the spleen and bone marrow which stain a sea-blue colour. It is sometimes considered a variant of niemann-pick disease.
(12 Dec 1998)
pyrrol blue C4OH3ON3O6Na;an acid triarylmethane dye employed as a vital dye and as an elastin stain.
Synonym: Isamine blue.
(05 Mar 2000)
sky blue A pigment mixture of cobaltous stannate and calcium sulfate; used biologically as an injection mass.
(05 Mar 2000)
nevus, blue A benign nevus, usually solitary, representing a localised proliferation of dermal melanocytes, which is manifested by a dark blue to black, moderately firm, rounded, sharply defined nodular tumour composed of spindle-shaped melanocytes with slender cytoplasmic processes, occurring often in association with melanin-laden macrophages in a sclerotic dermis. It is also called dermal melanocytoma and jadassohn-tieche nevus.
(12 Dec 1998)
new methylene blue A basic thiazin dye, C18H22N3SCl, used for supravital staining of reticulocytes in blood smears.
(05 Mar 2000)
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