| MAPK/ERK | Mitogen-activated protein kinase/extracellular-signal-regulated kinase |
|---|---|
| NDP kinase | Nucleoside diphosphate kinase |
| PI 3-kinase | Phosphatidylinositol 3'(OH)-kinase |
| Rho kinase | Rho-associated kinase |
| SAPK/JNK | Stress-activated protein kinase/c-Jun N-terminal kinase |
| MAP kinase | Mitogen activated protein kinases. (ERKs: externally regulated kinases) Serine threonine kinases that are activated when quiescent cells are treated with mitogens and therefore potentially transmit signal for entry into cell cycle. One target is trancription factor p62TCF. MAP kinase itself can be phosphorylated by MAP kinase kinase and this may in turn be controlled by RAF 1. Confusingly, do phosphorylate microtubule-associated proteins. (18 Nov 1997) |
|---|---|
| receptor protein-tyrosine kinase | <enzyme> A catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of receptors. Many growth and differentiation factor receptors contain this domain. It is critical for the signal transduction pathways required for mitogenesis, transformation, and cell differentiation. Registry number: EC 2.7.1.- (12 Dec 1998) |
| Receptors for activated C Kinase | Synonym for endosome. (18 Nov 1997) |
| receptor tyrosine kinase | Class of membrane receptors that phosphorylate tyrosine residues. Many play significant roles in development or cell division. Examples: insulin receptor family, c ros receptor, Drosophila sevenless, trk family. (18 Nov 1997) |
| geranylgeraniol kinase | <enzyme> A membrane-bound enzyme that catalyses the monophosphorylation of geranylgeraniol; isolated from sulfolobus acidocaldarius Registry number: EC 2.7.1.- Synonym: ggoh kinase (26 Jun 1999) |
| geranylgeranyl phosphate kinase | <enzyme> Cytosolic enzyme that catalyses phosphorylation of geranylgeraniol phosphate to yield geranylgeranyl diphosphate; isolated from sulfolobus acidocaldarius Registry number: EC 2.7.4.- Synonym: ggp kinase (26 Jun 1999) |
| germinal centre kinase | <enzyme> A human ste20 homolog; mw 97 kD; has been sequenced Registry number: EC 2.7.10.- Synonym: germinal centre kinase gck, gc kinase, bl44 gene product (26 Jun 1999) |
| casein kinase | <enzyme> Cyclic AMP has no effect; aspect of protein kinase, EC 2.7.1.37; there is a separate record for casein kinase II Registry number: EC 2.7.1.- Synonym: casein kinase I, casein kinase ts, casein g kinase, kappa casein kinase, g-box binding factor 1 kinase, gbf1 kinase, t-antigen kinase, orb5 gene product, protein kinase ck1, protein kinase cki, casein kinase ialpha, casein kinase ibeta, casein kinase igamma, yck1 protein, yck2 protein, yck3 gene product, casein kinase 1 epsilon, casein kinase 1 delta (26 Jun 1999) |
| vimentin kinase | <enzyme> 37 kD protein from bhk cells; phosphorylates vimentin at thr-457 and ser-458 in the c-terminal non-alpha-helical domain Registry number: EC 2.7.10.- (26 Jun 1999) |
| MCK1 protein kinase | <enzyme> From saccharomyces cerevisiae; involved in transcriptional activation of ime1, stimulation of spore maturation, and facilitation of centromere activity during mitosis; member of the glycogen synthase kinase 3 family; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: meiosis and centromere regulatory kinase, ypk1 phosphotyrosyl protein, ypk1 kinase, mck1 gene product (26 Jun 1999) |
| viomycin kinase | <enzyme> Vph from streptomyces vinaceus is involved in viomycin resistance; acts also on capreomycins; a serine residue in the peptide antibiotic acts as phosphate-acceptor Registry number: EC 2.7.1.103 Synonym: vph gene product, viomycin phosphotransferase (26 Jun 1999) |
| regulatory cell proliferation kinase | <enzyme> Involved in mitosis regulation; has characteristics of serine/threonine and tyrosine kinases; isolated from saccharomyces cerevisiae; genbank l08909 Registry number: EC 2.7.1.- Synonym: rpk1 protein, rpk1 gene product (26 Jun 1999) |
| pat1 protein kinase | <enzyme> Negatively regulated by mei3+ gene product Registry number: EC 2.7.1.- Synonym: ran1 protein (26 Jun 1999) |
| CCR1 protein kinase | <enzyme> Acts independently of camp-dependent protein kinase and the transcriptional activator adr1 in controlling yeast adh2 expression Registry number: EC 2.7.10.- Synonym: snf1 protein kinase, glc2 protein, glc2 gene product, snf1 gene product (26 Jun 1999) |
| cdc28 protein kinase | <enzyme> A protein kinase encoded by the saccharomyces cerevisiae cdc28 gene and required for progression from the g1 to the s phase in the cell cycle. It is a complex of approximately 160 kD containing a substrate called p40. Registry number: EC 2.7.1.- (12 Dec 1998) |