| penicillin phenoxymethyl | <chemical> (2s-(2 alpha,5 alpha,6 beta)-3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-4-thia-1- azabicyclo(3.2.0)heptane-2-carboxylic acid. A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms. Pharmacological action: penicillins. Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, (2S-(2alpha,5alpha,6beta))- (12 Dec 1998) |
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| penicillin resistance | <microbiology, pharmacology> Nonsusceptibility of an organism to the action of penicillins. (12 Dec 1998) |
| penicillin v | <chemical> (2s-(2 alpha,5 alpha,6 beta)-3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-4-thia-1- azabicyclo(3.2.0)heptane-2-carboxylic acid. A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms. Pharmacological action: penicillins. Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, (2S-(2alpha,5alpha,6beta))- (12 Dec 1998) |
| penicillin V benzathine | Benzathine phenoxymethylpenicillin;penicillin for oral use. (05 Mar 2000) |
| penicillin V hydrabamine | Hydrabamine phenoxymethylpenicillin;a compound with preparation and uses analogous to those of penicillin G hydrabamine. (05 Mar 2000) |
| penicillinase | <enzyme> Penicillin amino á lactamhydrolase: an enzyme produced by certain bacteria which converts penicillin to an inactive product and thus increases resistance to the antibiotic. A purified preparation from cultures of a strain of Bacillus cereus is used in treatment of reactions to penicillin. (18 Nov 1997) |
| penicillinate | A salt of a penicillic acid (i.e., of a penicillin). (05 Mar 2000) |
| penicillins | A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. A change in the nucleus will lead to a decrease in anti-bacterial activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (goodman and gilman's the pharmacological basis of therapeutics, 8th ed, p1065) (12 Dec 1998) |
| penicilliosis | Infection with fungi of the genus Penicillium and characterised in dogs by chronic sneezing and a nasal discharge. (05 Mar 2000) |
| Penicillium | A genus of fungi (class Ascomycetes, order Aspergillales), species of which yield various antibiotic substances and biologicals; e.g., citrinum yields citrinin; Penicillium claviforme, Penicillium expansum, and Penicillium patulum yield patulin; Penicillium chrysogenum yields penicillin; Penicillium griseofulvum yields griseofulvin; Penicillium notatum yields penicillin and notatin; Penicillium cyclopium and Penicillium puberulum yield penicillic acid; Penicillium purpurogenum and Penicillium rubrum yield rubratoxin. Penicillium marneffei is a true pathogen in Southeast Asia and in the bamboo rats. Origin: see penicillus (05 Mar 2000) |
| penicillium chrysogenum | A deuteromycetous fungal species used in the production of penicillin. (12 Dec 1998) |
| penicilloic acid | Alkali and bacterial degradation product of a penicillin, resulting from hydrolysis of the 1,7 bond. (05 Mar 2000) |
| penicilloyl polylysine | A preparation of polylysine and a penicillic acid, used intradermally in the diagnosis of penicillin sensitivity; sensitive persons may react with systemic manifestations, including generalised cutaneous eruptions. (05 Mar 2000) |
| penicillus | 1. One of the tufts formed by the repeated subdivision of the minute arterial twigs in the spleen. 2. In fungi, one of the branched conidiophores bearing chains of conidia in Penicillium species. Origin: L. Paint brush (05 Mar 2000) |
| penicin | An important precursor in the synthesis of penicillin derivatives. By itself, it has no antibiotic activity.For structure, see under penicillin in which R = H. Synonym: penicin. (05 Mar 2000) |