| nuclear RNA | <molecular biology> The nucleus contains RNA that has just been synthesised, but in addition there is some that seems not to be released or is only released after further processing, the heterogenous nuclear RNA (hnRNA) and small RNA molecules associated with protein to form small nuclear ribonucleoproteins. (18 Nov 1997) |
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| nuclear run off assay | <investigation, procedure> Technique for determining which genes are being actively transcribed at a given moment in an experiment by extracting nuclear material and allowing transcription to continue, then analysing the resulting RNAs. (18 Nov 1997) |
| nuclear sap | The presumably fluid substance or gel of the nucleus in which stainable elements were believed to be suspended; much that was formerly considered to be karyolymph is now known to be euchromatin. Synonym: nuclear hyaloplasm, nuclear sap, nucleochylema, nucleochyme. Origin: karyo-+ L. Lympha, clear water (05 Mar 2000) |
| nuclear scaffold serine protease | <enzyme> Calcium-regulated serine protease which cleaves a subset of lamins a/c (intermediate filament proteins) to produce an ATP-binding protein; partial amino-terminal amino acid sequence given in first source Registry number: EC 3.4.21.- Synonym: ns protease (26 Jun 1999) |
| nuclear scan: adrenals | A nuclear scan that images the adrenal glands after a radioactive tracer is injected into the bloodstream. This test is useful in detecting a pheochromocytoma, particularly if it not within the adrenal gland. (27 Sep 1997) |
| nuclear sclerosis | Increased refractivity of the central portion of the lens of the eye. See: nuclear cataract. (05 Mar 2000) |
| nuclear spindle | See: spindle and mitosis. (18 Nov 1997) |
| nuclear stain | <technique> A stain for cell nuclei, usually based on the binding of a basic dye to DNA or nucleohistone. (05 Mar 2000) |
| nuclear transplantation | <procedure> Experimental approach in study of nucleo cytoplasmic interactions, in which a nucleus is transferred from one cell to the cytoplasm (which may be anucleate) of a second. (18 Nov 1997) |
| nuclear transport | <cell biology> Passage of molecules in and out of the nucleus, presumably via nuclear pores. Passage of proteins into the nucleus may depend on possession of a nuclear location sequence containing five consecutive positively charged residues PKKKRKV). (18 Nov 1997) |
| nuclear warfare | Warfare involving the use of nuclear weapons. (12 Dec 1998) |
| nuclear-cytoplasmic ratio | Ratio of volume of nucleus to volume of cytoplasm, fairly constant for a particular cell type and usually increased in malignant neoplasms. (05 Mar 2000) |
| nuclease | <enzyme> An enzyme capable of cleaving the phosphodiester bonds between nucleotide subunits of nucleic acids. (18 Nov 1997) |
| nucleate | A salt of a nucleic acid. (05 Mar 2000) |
| nucleate endonuclease | A nuclease (a nucleate oligonucleotidohydrolase) that forms oligonucleotides ending in 5'-phosphates from RNA and DNA; hydrolyzes both double-stranded and single-stranded polynucleic acids. Synonym: nucleate endonuclease. (05 Mar 2000) |