| uroporphyrin-III C-methyltransferase | <enzyme> From pseudomonas denitrificans; enzyme of the cobalamin biosynthetic pathway which catalyses the c methylation of uroporphyrinogen III; also catalyses both nad+ dependent oxidation of precorrin-2 to sirohydrochlorin and insertion of iron into it to produce siroheme; cysg gene is from E coli; product of coba gene of pseudomonas; do not confuse with coba gene product of salmonella typhimurium which yields ATP-corrinoid adenosyltransferase Registry number: EC 2.1.1.107 Synonym: uroiii methyltransferase, uroporphyrinogen III methylase, sumt methyltransferase, s-adenosylmethionine-uroporphyrinogen III methyltransferase, cysg gene product, siroheme synthase, coba gene product, propionibacterium (26 Jun 1999) |
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| uroporphyrinogen-III synthase | <enzyme> An enzyme that catalyses the cyclization of hydroxymethylbilane to yield uroporphyrinogen III and water. Chemical name: Hydroxymethylbilane hydro-lyase (cyclizing) Registry number: EC 4.2.1.75 (12 Dec 1998) |
| forms of DNA i, II and III | Refers to circular DNA removed from viruses and as plasmids. Form I is the DNA in its normal, supercoiled form. Form II is the DNA after one of the two strands has been nicked (cut apart), and is circular. Form III is the DNA after both strands have been broken, and is linear. (09 Oct 1997) |
| Le Fort III craniofacial dysjunction | A complex fracture in which the facial bones are separated from the cranial bones. Synonym: Le Fort III craniofacial dysjunction, Le Fort III fracture, transverse facial fracture. (05 Mar 2000) |
| Le Fort III fracture | A complex fracture in which the facial bones are separated from the cranial bones. Synonym: Le Fort III craniofacial dysjunction, Le Fort III fracture, transverse facial fracture. (05 Mar 2000) |
| acrocephalosyndactyly type 1 | <paediatrics> An inherited disease (autosomal dominant) or a spontaneously occurring disease characterised by a peaked head and unusual facial appearance, due to the premature closure of the cranial sutures. A skull X-ray can confirm the diagnosis and treatment is surgical. Inheritance: autosomal dominant. (27 Sep 1997) |
| Alzheimer type I astrocyte | Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy. (05 Mar 2000) |
| Alzheimer type II astrocyte | Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease. (05 Mar 2000) |
| American Type Culture Collection | <cell culture> A key resource for cultured cells, located in Rockville, USA. (12 Dec 1998) |
| Antoni type A neurilemoma | <tumour> Relatively solid or compact arrangement of neoplastic tissue that consists of Schwann cells arranged in twisting bundles and associated with delicate reticulin fibres; the nuclei of the Schwann cells are frequently grouped in parallel rows (so-called palisades), and the nuclei and fibres sometimes form exaggerated tactile corpuscles, called Verocay bodies. (05 Mar 2000) |
| Antoni type B neurilemoma | <tumour> Relatively soft or loose arrangement of neoplastic tissue that consists of Schwann cells in a haphazard or nondescript type of arrangement among reticulin fibres and tiny cystlike foci; fat-laden macrophages may be observed in some of the larger neoplasms. (05 Mar 2000) |
| arthus-type reaction's | Reaction's in man and other species that result from the same basic immunologic (allergic) mechanism which evokes, in the rabbit, the typical Arthus phenomenon. See: immune complex disease. (05 Mar 2000) |
| avian adenovirus type 1 proteinase | <enzyme> 206 aa residues of which 66% are homologous to human ad2 emzyme embl/genbank l13161 Registry number: EC 3.4.22.- Synonym: aavl proteinase, aavl endopeptidase (26 Jun 1999) |
| basic personality type | An individual's unique, covert, or underlying personality propensities, whether or not they are behaviourally manifest or overt, personality characteristics of an individual which are also shared by a majority of the members of a social group. (05 Mar 2000) |
| Becker type muscular dystrophy | A muscular dystrophy that has many of the clinical features of Duchenne muscular dystrophy e.g., symmetrical involvement of first the pelvicrural muscles and then the pectoral girdle and proximal upper extremity muscles; pseudohypertrophy, especially of the calf muscles but with a much later age of onset (35-45 years), and more benign course. X-linked inheritance. (05 Mar 2000) |