| neurotrophic atrophy | Abnormalities of the skin, hair, nails, subcutaneous tissues and bone, caused by peripheral nerve lesions. Synonym: neuritic atrophy, neurogenic atrophy, neurotrophic atrophy, trophic changes. (05 Mar 2000) |
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| striate atrophy of skin | Bands of thin wrinkled skin, initially red but becoming purple and white, which occur commonly on the abdomen, buttocks, and thighs at puberty and/or during and following pregnancy, and result from atrophy of the dermis and overextension of the skin; also associated with ascites and Cushing's syndrome. Synonym: atrophoderma striatum, lineae albicantes, lineae atrophicae, linear atrophy, stretch marks, stria, striae atrophicae, striate atrophy of skin, traction atrophy, vergeture. (05 Mar 2000) |
| Sudeck's atrophy | Atrophy of bones, commonly of the carpal or tarsal bones, following a slight injury such as a sprain. See: causalgia, reflex sympathetic dystrophy. Synonym: acute reflex bone atrophy, posttraumatic osteoporosis, Sudeck's syndrome. Origin: L. English sweat (05 Mar 2000) |
| nutritional type cerebellar atrophy | A restricted type of cerebellar cortical degeneration, affecting particularly the Purkinje cells of the anterior and superior vermis; probably caused by thiamin deficiency; most frequently seen in chronic alcoholics and then called alcoholic cerebellar degeneration. (05 Mar 2000) |
| dentatorubral cerebellar atrophy with polymyoclonus | A familial disorder beginning in late childhood, characterised by progressive cerebellar ataxia, action myoclonus and preserved intellect. Probably due to multiple causes, mitochondrial abnormalities being one. Synonym: dentatorubral cerebellar atrophy with polymyoclonus. (05 Mar 2000) |
| diffuse brain atrophy | A form of dementia caused by destruction (atrophy) of the frontal lobes of the brain. This condition leads to the progressive deterioration of mental functioning. Incidence: 9 in 10,000 people in the general population. (27 Sep 1997) |
| disuse atrophy | Muscle wasting caused by immobilization, such as casting. (05 Mar 2000) |
| idiopathic muscular atrophy | A form of progressive muscular atrophy in which the disease begins in the muscle and not in the spinal centres. Synonym: Erb atrophy, idiopathic muscular atrophy. (05 Mar 2000) |
| infantile muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| infantile progressive spinal muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| infantile spinal muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| ischemic muscular atrophy | See: Volkmann's contracture. (05 Mar 2000) |
| olivopontocerebellar atrophy | A collection of diseases with atrophy of the cerebellum, pons, and inferior olives described in 1900 by dejerine and thomas. Signs and symptoms include ataxia of trunk and limbs, dysarthria, intention tremor, followed by generalised rigidity and dementia. (12 Dec 1998) |
| optic atrophy | Atrophy of the optic disk resulting from degeneration of the nerve fibres of the optic nerve and optic tract. (12 Dec 1998) |
| optic atrophy, hereditary | An inherited disorder in which optic atrophy is associated with muscle weakness, peroneal muscular atrophy and, in some patients, lancinating pains. In these patients the peripheral sensory neurons are probably affected. (12 Dec 1998) |