| neurofibrillary degeneration | Formation of coarse, argentophilic, intracytoplasmic fibres, often in complex tangles within intracranial nerve cells that are undergoing aging. See: Alzheimer's disease. (05 Mar 2000) |
|---|---|
| Nissl degeneration | Degeneration of the cell body occurring after transection of the axon; characterised by dispersion of the granular endoplasmic reticulum, swelling of the soma, and an eccentric position of the nucleus of the cell. (05 Mar 2000) |
| subacute combined degeneration of the spinal cord | A subacute or chronic disorder of the spinal cord, such as that occurring in certain patients with vitamin B12 deficiency, characterised by a slight to moderate degree of gliosis in association with spongiform degeneration of the posterior and lateral columns. Synonym: combined sclerosis, combined system disease, funicular myelitis, Putnam-Dana syndrome, vitamin B12 neuropathy. (05 Mar 2000) |
| degeneration | An effect whereby the productivity of a microbial strain used in a commercial process diminishes after repeated transfer from one culture media to another, often caused by genetic mutation. (14 Nov 1997) |
| descending degeneration | Orthograde (wallerian) degeneration of an injured nerve fibre; i.e., distal to the lesion, degeneration caudal to the level of a spinal cord lesion. (05 Mar 2000) |
| disciform degeneration | Foveal or parafoveal subretinal neovascularization with retinal separation and haemorrhage leading finally to a circular mass of fibrous tissue with marked loss of visual acuity. Synonym: disciform macular degeneration. (05 Mar 2000) |
| disciform macular degeneration | Foveal or parafoveal subretinal neovascularization with retinal separation and haemorrhage leading finally to a circular mass of fibrous tissue with marked loss of visual acuity. Synonym: disciform macular degeneration. (05 Mar 2000) |
| infantile neuronal degeneration | <neurology, paediatrics> Degenerative disorder of infants with widespread neuronal loss in thalamus, cerebellum, pons, and spinal cord, resembling infantile muscular atrophy. (05 Mar 2000) |
| olivopontocerebellar degeneration | <neurology> An inherited disease especially. Of mid to late life that is characterised by ataxia, hypotonia, dysarthria, and degeneration of the cerebellar cortex, middle cerebellar peduncles, and inferior olives. (09 Oct 1997) |
| orthograde degeneration | <medicine> A form of degeneration occurring in nerve fibres as a result of their division; so called from Dr. Waller, who published an account of it in 1850. Source: Websters Dictionary (01 Mar 1998) |
| tapetoretinal degeneration | A hereditary disorder of the retina mainly affecting photoreceptors and retinal pigment epithelium; a miscellaneous category including Friedreich's ataxia, Refsum's disease, and abetalipoproteinaemia. Synonym: primary pigmentary degeneration of retina. (05 Mar 2000) |
| Terrien's marginal degeneration | A form of marginal corneal degeneration. (05 Mar 2000) |
| ectatic marginal degeneration of cornea | Bilateral opacification and vascularization of the periphery of the cornea, progressing to formation of a gutter and ectasia. Synonym: ectatic marginal degeneration of cornea. (05 Mar 2000) |
| elastoid degeneration | 1. Degenerative change in elastic tissue. 2. Degeneration of collagen fibres, with altered staining properties resembling elastic tissue, or formation by fibroblast-activated ultraviolet or mast cell mediators of abnormal fibres. Synonym: elastoid degeneration, elastotic degeneration. (05 Mar 2000) |
| elastotic degeneration | 1. Degenerative change in elastic tissue. 2. Degeneration of collagen fibres, with altered staining properties resembling elastic tissue, or formation by fibroblast-activated ultraviolet or mast cell mediators of abnormal fibres. Synonym: elastoid degeneration, elastotic degeneration. (05 Mar 2000) |