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Mann's methyl blue-eosin stain <technique> A stain useful for anterior pituitary and viral inclusion bodies; a mixture of the two dyes stains alpha cell granules red, beta cell granules dark blue, chromophobes gray to pink, colloid red, erythrocytes orange-red, and collagen fibres blue; this method is also useful for enterochromaffin, goblet, Paneth, and pancreatic islet cells; Negri bodies appear red while their nuclei and central granules are blue.
(05 Mar 2000)
Victoria blue Any of several blue diphenylnaphthylmethane derivatives; used as a stain in histology.
Origin: Queen Victoria
(05 Mar 2000)
patent blue V A sulfonated triphenylmethane dye reduced and decolorised with zinc and acetic acid to produce a stable solution; used to demonstrate haemoglobin peroxidase.
Synonym: patent blue V.
(05 Mar 2000)
celestine blue B A dye recommended as a substitute for haematoxylin when it is unavailable.
(05 Mar 2000)
cellular blue nevus A large, acquired blue nevus in which melanocytes are often clear and large, alternating with pigmented spindle cells and which may expand deeply into the subcutis; malignant change is very rare.
(05 Mar 2000)
rhodanile blue A dye mixture, considered by some to be a salt of rhodamine B and Nile blue, used to stain keratinised epithelium (red) and fibroblasts (blue), as well as spermatozoa and normal and pathologic acidophilic, basophilic, and certain neutrophilic elements of cells and tissues; used as a substitute for haematoxylin and eosin.
(05 Mar 2000)
Perls' Prussian blue stain <technique> A stain for ferric iron as in haemosiderins, using potassium ferrocyanide in acetic acid or dilute hydrochloric acid followed by a red counterstain such as safranin O or neutral red; various haemosiderins and most mineral irons give a blue-green reaction, while nuclei stain red.
(05 Mar 2000)
methyl blue A sulfonated triphenylrosaniline dye used as a stain for cytoplasm, collagen, and Negri bodies, and as an antiseptic.
(05 Mar 2000)
Coomassie blue Stain commonly used non-specifically for proteins on gels. Recently renamed Kenacid Blue.
(18 Nov 1997)
Coomassie brilliant blue R-250 A general protein stain used in electrophoresis because of its unusual sensitivity.
Origin: originally, a proprietary name of Imperial Chemical; Coomassie (Kumasi), Ghana
(05 Mar 2000)
cresyl blue C17H20N3OCl; Aminodimethylaminoethyldiphenazonium chloride;a basic oxazin dye used for staining the reticulum in young erythrocytes (reticulocytes); also used in vital staining and as a selective stain for gastric surface epithelial mucin and other acid mucopolysaccharides.
(05 Mar 2000)
Prussian blue Fe4(Fe(CN)6)3; ferric ferrocyanide;a dye used to colour injection masses for blood vessels and lymphatics, and in staining of siderocytes.
Synonym: Prussian blue.
(05 Mar 2000)
prussian blue reaction The reaction of potassium ferrocyanide with ferric iron to yield a dark blue precipitate at the sites of the ferric iron. Used to determine ferric iron in tissues, particularly in the diagnosis of disorders of iron metabolism.
(12 Dec 1998)
Prussian blue stain <technique> A stain employing acid potassium ferrocyanide to demonstrate iron, as in siderocytes.
(05 Mar 2000)
sea-blue histiocyte A histiocyte containing cytoplasmic granules that stain bright blue with haematologic stains such as Wright-Giemsa; found in bone marrow and in the spleen, associated with hepatosplenomegaly and thrombocytopenic purpura and in other blood diseases.
(05 Mar 2000)
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