| AMPA | alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; American Medical Publishers Association |
|---|---|
| BAME | benzoylarginine methyl ester |
| CMME | chloromethyl methyl ether |
| COMT | catecholamine O-methyl transferase; certified ophthalmic medical technologist |
| DACM | N-(7-diamethylamino-4-methyl-3-coumarinyl) maleimide |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | <chemical> 1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine. A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in parkinson disease. These toxic effects can be prevented by the administration of selective monoamine oxidase inhibitors. Since the cellular toxicity of the compound is similar to that observed in idiopathic parkinson disease, experimental studies with this compound can suggest new opportunities for effective therapy. The compound also induces duodenal ulcers. Pharmacological action: dopamine agents. Chemical name: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl- (12 Dec 1998) |
|---|---|
| 1-methyl-4-phenylpyridinium | <chemical> 1-methyl-4-phenylpyridinium (mpp+). An active neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to paraquat, has also been used as an herbicide. Pharmacological action: dopamine agents, herbicides. Chemical name: Pyridinium, 1-methyl-4-phenyl- (12 Dec 1998) |
| 2-methyl branched-chain enoyl-CoA reductase | <enzyme> Important in the reversal of beta-oxidation under anaerobic conditions in ascaris suum Registry number: EC 1.3.1.52 Synonym: 2-methyl bce-CoA reductase (26 Jun 1999) |
| 3-(2,4--dioxo-6-methyl-5-pyrimidinyl)acrylic acid synthase | <enzyme> Involved in sparsomycin biosynthesis; catalyses conversion of 3-(4-oxo-6-methyl-5-pyrimidinyl)acrylic acid to 3-(2,4-dioxo-6-methyl-5-pyrimidinyl)acrylic acid Registry number: EC 1.14.13.- Synonym: (e)-uca synthase (26 Jun 1999) |
| (3-(5-methyl-2-thienyl)acryloyl)chymotrypsin | Pharmacological action: indicator and reagent Synonym: 3-mtac (26 Jun 1999) |
| 3-methyl-2-oxobutanoate hydroxymethyltransferase | <enzyme> Methylenetetrahydrofolate and alpha-ketoisovalerate gives tetrahydrofolate and ketopantoate Chemical name: 5,10-methylenetetrahydrofolate alpha-ketoisovalerate hydroxymethyltransferase Registry number: EC 2.1.2.11 Synonym: iphm transferase, panb protein, ketopantoate hydroxymethyltransferase (26 Jun 1999) |
| 3-O-methyl-fluorescein phosphatase | <enzyme> Used for assay of na-k-atpase in intact tissues Registry number: EC 3.6.1.- Synonym: 3-o-methylfluorescein phosphatase (26 Jun 1999) |
| (4-fluorophenyl)-alpha-methyl-5-benzoxazole methylamine | Amine derivative of flunoxaprofen. Pharmacological action: fluorescent dye Synonym: s-flopa (26 Jun 1999) |
| 4-methyl-3-hydroxyanthranilic acid adenylyltransferase | <enzyme> From streptomyces chrysomallus; catalyses the formation of 4-mha in the presence of ATP Registry number: EC 2.7.7.- Synonym: 4-mha activating enzyme (26 Jun 1999) |
| 4-methyl-5-nitrocatechol oxygenase | <enzyme> Catalyses conversion of 4-methyl-5-nitrocatechol to 2-hydroxy-5-methylquinone; dntb isolated from burkholderia; genbank u68411 Registry number: EC 1.13.12.- Synonym: mnc oxygenase, dntb gene product (26 Jun 1999) |
| 4-methylmuconolactone methyl-isomerase | <enzyme> From nocardioform actinomycetes; forms 3-methylmuconolactone Registry number: EC 5.3.3.- Synonym: 4-methyl-2-enelactone methylisomerase, mmlm-isomerase (26 Jun 1999) |
| 4-methyl sterol demethylase | <chemical> This term is used to describe 10 reactions in the collective processes of monooxygenation, decarboxylation and reduction, which, together account for the conversion of each of the two 4-methyl groups of lanosterol to carbon dioxide Chemical name: demethylase, methyl sterol Synonym: 4,4-dimethylzymosterol monooxygenase, sterol 4-demethylase (26 Jun 1999) |
| 4-toluene sulfonate methyl monooxygenase | <enzyme> From comamonas testosteroni t-2; catalyses the transformation of toluene sulfonate or p-toluate to the corresponding alcohol and the methyl side-chain to the corresponding acid in the presence of o2 and NADH; p- and m- toluates and 4-ethylbenzoate are substrates, whereas p-xylene, toluene and p-cresol are not substrates; enzyme also catalyses the demethylation of 4-methoxybenzoate to 4-hydroxybenzoate and formaldehyde; comprises reductase b and oxygenase m Registry number: EC 1.14.13.- Synonym: tsmoxygenase, tsmos, p-ts methyl-monooxygenase, tsam protein, tsab protein (26 Jun 1999) |
| absolute alcohol | Water having been removed. Synonym: anhydrous alcohol. (05 Mar 2000) |
| acyclic monoterpene primary alcohol - NADP oxidoreductase | <enzyme> From catmint nepeta racemosa; involved in the biosynthesis of iridoid monoterpenes; oxidises geraniol, nerol, and their 10-hydroxy derivatives in the presence of nadp(+). Registry number: EC 1.1.1.- Synonym: monoterpene primary alcohol - nadp oxidoreductase, ampano (26 Jun 1999) |