| PAM | pancreatic acinar mass; penicillin aluminum monostearate; peptidylglycine alpha-amidating monooxygen... |
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| PM | after death (Lat. post mortem); after noon [Lat. post meridiem]; mean pressure; pacemaker; pantomogr... |
| SM | Master of Science; sadomasochism; self-monitoring; silicon microphysiometer; simple mastectomy; skim... |
| TM | technology management; tectorial membrane; temperature by mouth; temporalis muscle; temporomandibula... |
| ANA | Anti-Nuclear Antibody |
| tropical medicine | <study> The branch of medicine concerned with diseases, mainly of parasitic origin, common in tropical and subtropical regions. (12 Dec 1998) |
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| evidence-based medicine | The process of systematically finding, appraising, and using contemporaneous research findings as the basis for clinical decisions. Evidence-based medicine asks questions, finds and appraises the relevant data, and harnesses that information for everyday clinical practice. Evidence-based medicine follows four steps: formulate a clear clinical question from a patient's problem; search the literature for relevant clinical articles; evaluate (critically appraise) the evidence for its validity and usefulness; implement useful findings in clinical practice. The term "evidence based medicine" (no hyphen) was coined at mcmaster medical school in canada in the 1980's to label this clinical learning strategy, which people at the school had been developing for over a decade. (12 Dec 1998) |
| experimental medicine | The scientific investigation of medical problems by experimentation upon animals or by clinical research. (05 Mar 2000) |
| family medicine | The medical specialty concerned with providing continuous, comprehensive care to all age groups, from first patient contact to terminal care, with special emphasis on care of the family as a unit. (05 Mar 2000) |
| foetal medicine | Study of the growth, development, care, and treatment of the foetus, and of environmental factors harmful to the foetus. Synonym: fetology. (05 Mar 2000) |
| folk medicine | Treatment of ailments outside of organised medicine by remedies and simple measures based upon experience and knowledge handed on from generation to generation. (05 Mar 2000) |
| forensic medicine | The application of medical knowledge to questions of law. (12 Dec 1998) |
| legal medicine | The application of medical knowledge to questions of law. (12 Dec 1998) |
| receptors, cytoplasmic and nuclear | Proteins in the cytoplasm or nucleus that specifically bind signalling molecules and trigger changes which influence the behaviour of cells. The major groups are the steroid hormone receptors, which usually are found in the cytoplasm, and the thyroid hormone receptors, which usually are found in the nucleus. Receptors, unlike enzymes, generally do not catalyze chemical changes in their ligands. (12 Dec 1998) |
| Remak's nuclear division | <cell biology> An unusual form of nuclear division, in which the nucleus simply constricts, rather like a cell without chromosome condensation or spindle formation. Partitioning of daughter chromosomes is haphazard. Observed in some Protozoa. (18 Nov 1997) |
| Pelger-Huet nuclear anomaly | Congenital inhibition of lobulation in the nuclei of neutrophilic leukocytes; most cells present band or bilobulate appearance, and only an occasional cell is trilobed; it is not associated with disease, but may be confused with leukocyte "shift to left"; autosomal dominant inheritance. (05 Mar 2000) |
| ribonucleoproteins, small nuclear | Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, including pre-mRNA splicing and pre-mRNA 3'-end processing in the nucleoplasm. The u3 snrnp is localised in the nucleolus, where it aligns into base pairs with the 28s rrna precursor in a still unidentified region and functions in pre-rrna processing. The u7 snrnp aligns into base pairs with a conserved sequence in the 3'-end of histone pre-mRNA and is an essential cofactor for the cleavage that creates the mature nonadenylated 3'-end. (12 Dec 1998) |
| RNA, heterogeneous nuclear | Nuclear nonribosomal RNA larger than about 1000 nucleotides, the mass of which is rapidly synthesised and degraded within the cell nucleus. Some heterogeneous nuclear RNA may be a precursor to mRNA. However, the great bulk of total hnrna hybridises with nuclear DNA rather than with mRNA. (12 Dec 1998) |
| RNA, nuclear | RNA molecules found in the nucleus either associated with chromosomes or in the nucleoplasm. (12 Dec 1998) |
| RNA, small nuclear | Short chains of RNA found in the nucleus. Their function is to remove the introns (nontranslated intervening sequences) from mRNA precursors, thereby bringing the two exons (coding segments) together into correct juxtaposition for enzymatic splicing at the correct point. The resulting mRNA is now ready to leave the nucleus. (12 Dec 1998) |