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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 5
  • Mitogen-Activated Protein Kinase 14 - »õâ A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
    Synonyms : CSAID-Binding Protein, Cytokine Suppressive Anti-inflammatory Drug Binding Protein, Kinase CSBP, MAPK14, MAPK14 Mitogen-Activated Protein Kinase, MAX-Interacting Protein 2, Mxi2 Protein, SAPK2a, Stress-activated protein kinase 2a, p38alpha MAP Kinase
  • Mitogen-Activated Protein Kinase 3 - »õâ A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.
    Synonyms : ERK1 Kinase, MAPK3 Mitogen-Activated Protein Kinase, Meiosis-Activated Myelin Basic Protein Kinase p44(mpk), Microtubule-Associated Protein-2 Kinase, PSTkinase p44mpk, Protein-Serine-Threonine Kinase p44(mpk), p44 MAPK, Extracellular Signal Regulated Kinase 1
  • Mitogen-Activated Protein Kinase 6 - »õâ A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX.
    Synonyms : ERK3 Kinase, MAPK6 Mitogen-Activated Protein Kinase, p97(MAPK) Protein, p97MAPK Protein, Extracellular Signal Regulated Kinase 3, Kinase, ERK3, MAPK6 Mitogen Activated Protein Kinase, Mitogen Activated Protein Kinase 6
  • Mitogen-Activated Protein Kinase 7 - »õâ A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress and by GROWTH FACTOR RECEPTORS-mediated pathways.
    Synonyms : BMK1 Kinase, Big MAP Kinase 1, ERK5 Kinase, MAPK7 Mitogen-Activated Protein Kinase, Mitogen-Activated Protein Kinase 7 Isoform 1, Mitogen-Activated Protein Kinase 7 Isoform 2, Extracellular Signal Regulated Kinase 5, Kinase, BMK1, Kinase, ERK5
  • Mitogen-Activated Protein Kinase 8 - »õâ A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING.
    Synonyms : JNK1 Kinase, MAPK8 Mitogen-Activated Protein Kinase, SAP Kinase-1, SAPK1 Mitogen-Activated Protein Kinase, Stress-Activated Protein Kinase 1, Stress-Activated Protein Kinase JNK1, Stress-Activated Protein Kinase gamma, c-jun Kinase-1, c-jun N-Terminal Kinase 1
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mitotic index In a population of cells, the ratio of the number of cells undergoing mitosis (cell division) to the number of cells not undergoing mitosis.
Ãâó: www.stjude.org/glossary
mitotic inhibitor A drug that inhibits cell growth by stopping cell division. Mitotic inhibitors are used as treatments for cancer. Also called antimitotic or antimicrotubule agents and taxanes. Docetaxel and paclitaxel are mitotic inhibitors.
Ãâó: www.stjude.org/glossary
mitochondrion (Gr. mitos, thread + chondrion, a grain; pl: mitochondria) A small cytoplasmic organelle that carries out aerobic respiration. Oxidative phosphorylation takes place to produce ATP.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E16.htm
mitosis (Gr. mitos, a thread; adj: mitotic; pl: mitoses) Disjunction of replicated chromosomes and division of the cytoplasm to produce two genetically identical daughter cells. The division involves the appearance of chromosomes, their longitudinal duplication, and equal distribution of newly formed parts to daughter nuclei. It is separated into five stages: interphase, prophase, metaphase, anaphase and telophase.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E16.htm
mitotic index The percentage of cells in the mitotic phase of the cell cycle.
Ãâó: www.nature.com/nrg/journal/v5/n1/glossary/nrg1248_...
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