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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 5
  • Integrin alphaXbeta2 - »õâ A major adhesion-associated heterodimer molecule expressed by MONOCYTES; GRANULOCYTES; NK CELLS; and some LYMPHOCYTES. The alpha subunit is the CD11C ANTIGEN, a surface antigen expressed on some myeloid cells. The beta subunit is the CD18 ANTIGEN.
    Synonyms : CR4 Receptor, Complement Receptor 4, Complement Receptor Type 4, Neutrophil GP150, Neutrophil Glycoprotein Gp150, Receptor, CR4, alphaXbeta2 Integrin, p150, 95 Glycoprotein, Antigen, p150, 95, GP150, Neutrophil, Glycoprotein Gp150, Neutrophil, Glycoprotein, p150, 95
  • Integrin beta Chains - »õâ Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.
    Synonyms : Integrin beta Subunits, Integrins, beta, beta Chains, Integrin
  • Integrin beta3 - »õâ An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.
    Synonyms : CD61 Antigen, GPIIIa, Platelet GPIIIa, Platelet Glycoprotein IIIa, beta(3) Integrin, beta3 Integrin, beta3A Integrin, beta3B Integrin, beta3C Integrin, Antigen, CD61, Glycoprotein IIIa, Platelet, Integrin, beta3, Integrin, beta3A, Integrin, beta3B, Integrin, beta3C
  • Integrin beta4 - »õâ Also known as CD104 antigen, this protein is distinguished from other beta integrins by its relatively long cytoplasmic domain (approximately 1000 amino acids vs. approximately 50). Five alternatively spliced isoforms have been described.
    Synonyms : CD104 Antigen, Integrin beta(4), beta4 Integrin, Antigen, CD104, Integrin, beta4, beta4, Integrin
  • Integrins - »õâ A family of transmembrane glycoproteins (MEMBRANE GLYCOPROTEINS) consisting of noncovalent heterodimers. They interact with a wide variety of ligands including EXTRACELLULAR MATRIX PROTEINS; COMPLEMENT, and other cells, while their intracellular domains interact with the CYTOSKELETON. The integrins consist of at least three identified families: the cytoadhesin receptors(RECEPTORS, CYTOADHESIN), the leukocyte adhesion receptors (RECEPTORS, LEUKOCYTE ADHESION), and the VERY LATE ANTIGEN RECEPTORS. Each family contains a common beta-subunit (INTEGRIN BETA CHAINS) combined with one or more distinct alpha-subunits (INTEGRIN ALPHA CHAINS). These receptors participate in cell-matrix and cell-cell adhesion in many physiologically important processes, including embryological development; HEMOSTASIS; THROMBOSIS; WOUND HEALING; immune and nonimmune defense mechanisms; and oncogenic transformation.
    Synonyms :
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 5
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