| cold liver lesion | <radiology> Size for detection = 1-2 cm (3-cm deep lesions), primary tumour (haemangioma hot by Tc-RBCs), metastasis, inflammatory lesion (e.g., amebic abscess), degenerative disease, trauma, congenital lesion (solitary cyst or polycystic disease) see: liver-spleen scan (12 Dec 1998) |
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| cold nodule | A thyroid nodule with a much lower uptake of radioactive iodine than the surrounding parenchyma; about one in four prove to be malignant. (05 Mar 2000) |
| cold pressed | <technique> A more natural process by which vegetable oils are produced to yield greater nutrient value. Cold pressing does not use heat or chemicals that commercial pressing does. (27 Sep 1997) |
| cold pressor test | A cardiocirculatory challenge conventionally performed by immersing one hand in ice cold water for two or more minutes (as tolerated) to acutely raise the blood pressure, thus imposing resistance to ejection of blood from the left ventricle into the systemic arterial system and consequently acutely increased afterload (afterload = increased left ventricular wall stress). Synonym: Hines-Brown test. (05 Mar 2000) |
| cold processed | <technique> A process by which chemicals are used to extract vegetable oils. The chemicals are later filtered out. (27 Sep 1997) |
| cold-reactive antibody | See: cold agglutinin. (05 Mar 2000) |
| cold-rigor point | The degree of lowered temperature at which the activity of a cell ceases and the cell passes into the narcotic or hibernating state. (05 Mar 2000) |
| cold sensitive enzyme | <enzyme> An enzyme that loses its stability as the temperature is lowered. (05 Mar 2000) |
| cold-sensitive mutant | A mutant that is defective at low temperature but functional at normal temperature. Compare: temperature-sensitive mutant. (05 Mar 2000) |
| cold sore | <dermatology, virology> An infection of the lips or mouth which results in a blistery sore that is caused by Herpes simplex type 1. Painful blisters (eventually becoming ulcers) will often presenting on the lips or nasal mucosa. Infected individuals should avoid contact with others due to potential for transfer of the infection. Herpes labialis tends to be recurrent and often exacerbated by stress, sunlight, fever or illness. Treatment includes the use of antiviral creams (acyclovir) and oral medications (acyclovir). Pre-treatment with oral acyclovir, in those prone to cold sores (prior to sun exposure, etc.) has been shown to decrease exacerbations. (27 Sep 1997) |
| cold spleen lesion | <radiology> Infarction, lymphoma, haematoma, tumour, splenic artery aneurysm, pancreatic pseudocyst, variant, artifact, absent spleen, splenectomy, sickle cell disease, trauma see: liver-spleen scan (12 Dec 1998) |
| cold stage | The stage of chill in a malarial paroxysm. (05 Mar 2000) |
| cold thyroid nodule | <radiology> Adenoma (75%), colloid cyst (10%), carcinoma (15%), mnemonic: CATCH PALLM colloid cyst, adenoma, thyroiditis, carcinoma, haematoma, parathyroid adenoma, abscess, lymph node, lymphoma, metastasis thyroid carcinoma, hot thyroid nodule (12 Dec 1998) |
| cold ulcer | A small gangrenous ulcer on the extremities; due to defective circulation. (05 Mar 2000) |
| cold urticaria | Wheal formation that develops after exposure to lowered temperatures, with or without demonstrable passive-transfer antibodies. Synonym: congelation urticaria. (05 Mar 2000) |