| DNA probes, HLA | DNA probes specific for the human leukocyte antigen genes, which represent the major histocompatibility determinants in humans. The four known loci are designated as a, b, c, and d. Specific antigens are identified by a locus notation and number, e.g., HLA-a11. The inheritance of certain HLA alleles is associated with increased risk for certain diseases (e.g., insulin-dependent diabetes mellitus). (12 Dec 1998) |
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| DNA probes, HPV | DNA probes specific for the identification of human papilloma virus. (12 Dec 1998) |
| DNA profiling | <molecular biology> See restriction fragment length polymorphism. (18 Nov 1997) |
| DNA puff | <molecular biology> An area on a chromosome where transcription of DNA into mRNA, or replication of DNA is occurring, resulting in an enlarged, puffy appearance of the area. Similar to chromosome puff, except generalised to any type of chromosome in any type of organism. (09 Oct 1997) |
| DNA rearrangement | <molecular biology> Wholesale movement of sequences from one position to another in DNA, such as occur somatically, for example in the generation of antibody diversity. (18 Nov 1997) |
| DNA renaturation | <molecular biology> The reformation of double stranded DNA from thermally denatured DNA. The rate of reassociation depends upon the degree of repetition and is slowest for unique sequences (this is the basis of the Cot value). (18 Nov 1997) |
| DNA repair | <molecular biology> Each cell has a series of special enzymes to correct the errors in DNA structure and sequence. This protects genetic information against environmental damage and replication errors and restore the DNA to its original state. (25 Jun 1999) |
| DNA repair gene | A gene engaged in DNA repair. When a DNA repair gene is altered, mutations pile up throughout the DNA. (12 Dec 1998) |
| DNA repair pathway | The sequence of steps in the repair of DNA. Each step is governed by an enzyme. (12 Dec 1998) |
| DNA replicase | <enzyme> An aspect of EC 2.7.7.7; mouse enzyme has both DNA polymerase and DNA primase activity Registry number: EC 2.7.7.- (26 Jun 1999) |
| DNA replication | <molecular biology> The process whereby a copy of a DNA molecule is made and thus the genetic information it contains is duplicated. The parental double stranded DNA molecule is replicated semi conservatively, i.e. Each copy contains one of the original strands paired with a newly synthesised strand that is complementary in terms of at and GC base pairing. Though in this sense conceptually simple, mechanistically a complex process involving a number of enzymes. (18 Nov 1997) |
| DNA restriction enzymes | <enzyme> Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of dnas, and have made it possible to splice and recombine genes from one organism into the genome of another. Registry number: EC 3.1.21 (12 Dec 1998) |
| DNA restriction-modification enzymes | Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage. (12 Dec 1998) |
| DNA reverse gyrase | <enzyme> A topoisomerase II subclass which introduces positive superhelical turns into DNA Registry number: EC 3.1.- Synonym: reverse gyrase (26 Jun 1999) |
| DNA sequence | <molecular biology> The relative order of base pairs, whether in a fragment of DNA, a gene, a chromosome, or an entire genome. See: base sequence analysis. (09 Oct 1997) |
| superhelical DNA endonuclease | <enzyme> Produces single nicks in superhelical DNA; co-purifies with calf thymus terminal deoxynucleotidyl transferase Registry number: EC 3.1.21.- (26 Jun 1999) |
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| Deep Vent DNA polymerase | <enzyme> A thermostable DNA polymerase with putative proofreading activity Registry number: EC 2.7.7.- (26 Jun 1999) |
| denaturation temperature of DNA | That temperature at which, under a given set of conditions, double-stranded DNA is changed (50%) to single-stranded DNA; under standard conditions, the base composition of the DNA can be estimated from the denaturation temperature, since the greater the denaturation temperature, the greater the guanine-plus-cytosine content (i.e., GC content) of the DNA. Synonym: melting temperature of DNA. (05 Mar 2000) |
| double-stranded complimentary DNA | <molecular biology> A duplex DNA molecule copied from a copy DNA template. (09 Oct 1997) |
| dyad symmetry of DNA | <molecular biology> Two areas of a DNA molecule whose base pair sequences are repeats of each other, inverted relative to each other, or are palindromes. (09 Oct 1997) |
| O(2)-methylthymine-DNA glycosidase | <enzyme> Repairs o(2)-methylthymidine residues in DNA Registry number: EC 3.2.2.- Synonym: mth-DNA glycosidase (26 Jun 1999) |
| O(4)-methylthymine-DNA methyltransferase | <enzyme> Repairs o(4)-methylthymidine residues in DNA Registry number: EC 2.1.1.- Synonym: mth-DNA methyltransferase (26 Jun 1999) |
| o(6)-methylguanine-DNA methyltransferase | <enzyme> An enzyme that transfers methyl groups from o(6)-methylguanine, and other methylated moities of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction. Chemical name: DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase Registry number: EC 2.1.1.63 (12 Dec 1998) |
| technology, recombinant DNA | A series of procedures used to join together (recombine) DNA segments. A recombinant DNA molecule is constructed (recombined) from segments from 2 or more different DNA molecules. Under certain conditions, a recombinant DNA molecule can enter a cell and replicate there, autonomously (on its own) or after it has become integrated into a chromosome. (12 Dec 1998) |
| Tet DNA polymerase | <enzyme> From thermus thermophilus; thermostable, used as a replacement for taq polymerase in DNA sequencing Registry number: EC 2.7.7.- Synonym: DNA polymerase tet (26 Jun 1999) |
| transfer DNA | <molecular biology> The transforming region of DNA in the Ti plasmid of agrobacterium tumefaciens. Acronym: t-DNA (04 Jul 1999) |
| triple DNA | <molecular biology> A variation of DNA, in which there is a third strand of nucleotides binding to the first two by specific base pairing. (14 Nov 1997) |
| exogenous DNA | <molecular biology> DNA originating outside an organism. (09 Oct 1997) |
| junk DNA | That portion of DNA which is not transcribed and expressed, comprising about 90% of the 3 billion base pairs of the human genome; its function is not known. (05 Mar 2000) |
| extrachromosomal DNA | DNA that occurs naturally outside of the nucleus (e.g., mitochondrial DNA). (05 Mar 2000) |
Synonyms : Nucleotidyltransferases, DNA
Synonyms : Packaging, DNA
Synonyms : IV, DNA Polymerase, Polymerase IV, DNA, Polymerase beta, DNA
Synonyms : DNA Dependent DNA Polymerase I, Polymerase I, DNA, Polymerase alpha, DNA
Synonyms : DNA Dependent DNA Polymerase II, Polymerase II, DNA, Polymerase epsilon, DNA
| DNA polymerase |
An enzyme that catalyzes the polymerization of successive nucleotides during replication of DNA.
출처: www.knowledgebank.irri.org/glossary/Glossary/D.htm
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| DNA |
Deoxyribonucleic acid. The molecules inside cells that carry genetic information and pass it from one generation to the next.
출처: www.seniormag.com/conditions/cancer/cancerglossary...
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| DNA ligase |
an enzyme which repairs breaks in the phosphate backbone of DNA.
출처: www.mycolog.com/GLOSSARY.htm
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| DNA |
DNA is the constituent of chromosomes which stores the hereditary information in the form of a sequence of nitrogenous bases. Much of this information relates to the synthesis of proteins.
출처: www.bio.hw.ac.uk/edintox/glossall.htm
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| DNA ligase |
In recombinant DNA technology, an enzyme that seals together two DNA fragments from different sources to form a recombinant DNA molecule.
출처: www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBook...
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