| deficiency symptom | Manifestation of a lack, in varying degrees, of some substance (e.g., hormone, enzyme, vitamin) necessary for normal structure and/or function of an organism. (05 Mar 2000) |
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| deficiency, alpha-1 antitrypsin | An inherited disease with little or no production of an important protein, alpha-1 antitrypsin. The lack of this protein leads to damage of various organs, mainly the lung and liver. The disease may become apparent at a very early age or in adulthood, as shortness of breath or liver-related symptoms (jaundice, fatigue, fluid in the abdomen, mental changes, or gastrointestinal bleeding). There are several options for treatment of the lung disease, including replacement of the missing protein. Treatment of the liver disease is a well-timed liver transplant (12 Dec 1998) |
| deficiency, calcium | A low blood calcium (hypocalcaemia). Hypocalcaemia makes the nervous system highly irritable with tetany (spasms of the hands and feet, muscle cramps, abdominal cramps, overly active reflexes, etc.). Chronic calcium deficiency contributes to poor mineralization of bones, soft bones (osteomalacia) and osteoporosis; and, in children, rickets and impaired growth. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1 gram daily for both men and women. The upper limit for calcium intake is 2.5 grams daily. (12 Dec 1998) |
| deficiency, glucocerebrosidase | Causes Gaucher's disease (type 1), a progressive genetic disease, due to an enzyme defect. The enzyme, glucocerebrosidase, is needed to break down the chemical glucocerebroside. The enzyme defect in persons with Gaucher's disease (GD) leads to the accumulation of glucocerebroside in the spleen, liver, and lymph nodes. The most common early sign is enlargement of the spleen (located in the upper left abdomen). Other signs include low red blood cell counts (anaemia), a decrease in blood clotting cells (platelets), increased pigmentation of the skin, and a yellow fatty spot on the white of the eye (a pinguecula). Severe bone involvement can lead to pain and collapse of the bone of the hips, shoulders, and spine. The GD gene is on chromosome 1. The disease is a recessive trait. Both parents carry a GD gene and transmit it for their child with the disease. The parents' risk of a child with the disease is 1 in 4 with each pregnancy. This type of Gaucher's disease (noncerebral juvenile Gaucher's disease) is most common in Ashkenazi Jews (of European origin) and is the most common genetic disease among Jews in the United States. (12 Dec 1998) |
| deficiency, glucose-6-phosphate dehydrogenase | Deficiency of G6PD is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The G6PD gene is on the X chromosome. Males with the enzyme deficiency develop anaemia due to breakup of their red blood cells when they are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. (12 Dec 1998) |
| deficiency, iron | Deficiency of iron results in anaemia because iron is necessary to make haemoglobin, the key molecule in red blood cells responsible for the transport of oxygen. In iron deficiency anaemia, the red cells are unusally small (microcytic) and pale (hypochromic). Characteristic features of iron deficiency anaemia in children include failure to thrive (grow) and increased infections. The treatment of iron deficiency anaemia , whether it be in children or adults, is with iron and iron-containing foods. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. (12 Dec 1998) |
| deficiency, lactase | Lack of the enzyme lactase resulting in failure to digest lactose in milk (lactose intolerance). (12 Dec 1998) |
| deficiency, magnesium | Can occur due to inadequate intake or impaired intestinal absorption of magnesium. Low magnesium (hypomagnesaemia) is often associated with low calcium (hypocalcaemia) and potassium (hypokalaemia) levels. Deficiency of magnesium causes increased irritability of the nervous system with tetany (spasms of the hands and feet, muscular twitching and cramps, spasm of the larynx, etc.). According to the National Academy of Sciences, the Recommended Dietary Allowances of magnesium are 420milligrams per day for men and 320 milligrams per day for women. The upperlimit of magnesium as supplements is 350 milligrams daily, in addition to the magnesium from food and water. (12 Dec 1998) |
| deficiency, protein c | Protein C is a protein in plasma that enters into the cascade of biochemical events leading to the formation of a clot. Deficiency of protein C results in thrombotic (clotting) disease. (12 Dec 1998) |
| deficiency, selenium | Deficiency of the essential mineral selenium causes Keshan disease, a fatal form of cardiomyopathy (disease of the heart muscle) first observed in Keshan province in China and since found elsewhere. According to the National Academy of Sciences, the Recommended Dietary Allowances of selenium are 70 milligrams per day for men and 55 milligrams per day for women. Food sources of selenium include seafoods, some meats such as kidney and liver, and some grains and seeds. (12 Dec 1998) |
| deficiency, zinc | Deficiency of zinc is associated with short stature, anaemia, increased pigmentation of skin (hyperpigmentation), enlarged liver and spleen (hepatosplenomegaly), impaired gonadal function (hypogonadism), impaired wound healing, and immune deficiency. (For a genetic disorder that impairs zinc uptake, please see Acrodermatitis enteropathica). According to the National Academy of Sciences, the Recommended Dietary Allowances of zinc are 12 milligrams per day for women and 10 milligrams per day for men. Food sources of zinc include meat including liver, eggs, seafood, nuts and cereal. (12 Dec 1998) |
| deficient | Wanting, to make up completeness; wanting, as regards a requirement; not sufficient; inadequate; defective; imperfect; incomplete; lacking; as, deficient parts; deficient estate; deficient strength; deficient in judgment. "The style was indeed deficient in ease and variety." (Macaulay) Deficient number. <mathematics> See Abundant. Defi"cient-ly. Origin: L. Deficiens, -entis, p. Pr. Of deficere to be wanting. See Defect. Source: Websters Dictionary (01 Mar 1998) |
| deficit | A lack or deficiency. (18 Nov 1997) |
| defilement | The act of defiling, or state of being defiled, whether physically or morally; pollution; foulness; dirtiness; uncleanness. "Defilements of the flesh." (Hopkins) "The chaste can not rake into such filth without danger of defilement." (Addison) Origin: From Defile. Source: Websters Dictionary (01 Mar 1998) |
| define | 1. To fix the bounds of; to bring to a termination; to end. "To define controversies." 2. To determine or clearly exhibit the boundaries of; to mark the limits of; as, to define the extent of a kingdom or country. 3. To determine with precision; to mark out with distinctness; to ascertain or exhibit clearly; as, the defining power of an optical instrument. "Rings . . . Very distinct and well defined." (Sir I. Newton) 4. To determine the precise signification of; to fix the meaning of; to describe accurately; to explain; to expound or interpret; as, to define a word, a phrase, or a scientific term. "They define virtue to be life ordered according to nature." (Robynson (More's Utopia)) Origin: OE. Definer, usually, to end, to finish, F. Definir to define, L. Definire to limit, define; de- + finire to limit, end, finis boundary, limit, end. See Final, Finish. Source: Websters Dictionary (01 Mar 1998) |
| defecate |
stool: have a bowel movement; "The dog had made in the flower beds"
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| defibrillate |
stop the fibrillation and restore normal contractions, usually by means of electric shocks; "The patient's heart had to be defibrillated to save his life"
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| defibrinate |
remove fibrin from (blood)
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| deficient |
inadequate in amount or degree; "a deficient education"; "deficient in common sense"; "lacking in stamina"; "tested and found wanting" insufficient: of a quantity not able to fulfill a need or requirement; "insufficient funds" falling short of some prescribed norm; "substandard housing"
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| defibrillator |
an electronic device that administers an electric shock of preset voltage to the heart through the chest wall in an attempt to restore the normal rhythm of the heart during ventricular fibrillation
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| DEF | markedly subnormal in structure or function or intelligence or behavior |
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| DEF | having a defect |
| DEF | any pleading that fails to conform in form or substance to minimum standards of accuracy or sufficiency |
| DEF | in a defective manner |
| DEF | the state of being defective |
| DEF | a person who abandons their duty (as on a military post) |
| DEF | remove the ovaries of |
| DEF | remove the ovaries of |
| DEF | protection from harm |
| DEF | military action or resources protecting a country against potential enemies |
| DEF | a defendant's answer or plea denying the truth of the charges against him |
| DEF | a structure used for defense |