| Coats' disease | Retinitis exudativa, a chronic abnormality characterised by deposition of cholesterol and cholesterol esters in outer retinal layers and subretinal space. In adults, often preceded by uveitis; in children, often preceded by retinal vascular abnormalities. Synonym: Coats' disease. (05 Mar 2000) |
|---|---|
| Coats, George | <person> British ophthalmologist, 1876-1915. See: Coats' disease. (05 Mar 2000) |
| cob(I)alamin adenosyltransferase | <enzyme> Product of cbla gene; deficiency results in some forms of methylmalonic aciduria Registry number: EC 2.5.1.17 Synonym: vitamin b12s adenosyltransferase, vitamin b12s adenosylating enzyme, deoxyadenosyltransferase (26 Jun 1999) |
| cob(II)yrinic acid a,c-diamide reductase | <enzyme> Nadh-dependent flavoenzyme which reduces the cobalt of cob(ii)yrinic acid a,c-diamide to cobalt (i) Registry number: EC 1.6.99.- Synonym: cobyrinic acid a,c-diamide reductase, co ac-a,c-d reductase (26 Jun 1999) |
| cobalamin | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| cobalamin (5'-phosphate)synthase | <enzyme> From pseudomonas denitrificans; catalyses the synthesis of cobalamin 5'-phosphate from GDP-cobinamide and alpha-ribazole 5'-phosphate, but also the synthesis of cobalamin from GDP-cobinamide and alpha-ribazole Registry number: EC 2.6.99.- Synonym: cobv gene product (26 Jun 1999) |
| cobalamin concentrate | The dried, partially purified product resulting from the growth of selected Streptomyces cultures or other cobalamin-producing microorganisms; contains at least 500 ug of cobalamin in each gram. (05 Mar 2000) |
| cobalt | <chemical> A trace element that is a component of vitamin b12. It has the atomic symbol co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anaemia; its excess in humans can lead to erythrocytosis. Chemical name: Cobalt (12 Dec 1998) |
| cobalt isotopes | <radiobiology, physics> Stable cobalt atoms that have the same atomic number as the element cobalt, but differ in atomic weight. Co-59 is a stable cobalt isotope. (12 Dec 1998) |
| cobalt machine | <apparatus> A simple but effective source of irradiation which is employed for external beam radiotherapy. It has limited ability to focus irradiation. (16 Dec 1997) |
| cobalt radioisotopes | Unstable isotopes of cobalt that decay or disintegrate emitting radiation. Co atoms with atomic weights of 54-64, except 59, are radioactive cobalt isotopes. (12 Dec 1998) |
| cobalt-57 | <radiobiology> A radioisotope with a half-life of 271.8 days. It decays by electron capture with emission of a medium energy (122.06 keV) gamma ray. Used as a diagnostic aid with some metabolic disorders. (17 Jul 2002) |
| cobalt-58 | <radiobiology> Positron emitter with half-life of 70.88 days. (05 Mar 2000) |
| cobalt-60 | <radiobiology> A radioisotope with a half-life of 5.271 years. It emits beta particles and energetic gamma rays, for which reason it is used in radiation therapy and diagnostics in place of radium or X-rays. It is also used as a diagnostic aid in vitamin B12-related problems. (05 Mar 2000) |
| cobaltochelatase | <enzyme> Incorporates co(ii) into porphyrins Registry number: EC 4.99.1.- Synonym: co(ii)-chelatase (26 Jun 1999) |