| botulinum antitoxin | An equine antitoxin against the toxins produced by the type a, b, or e strain of clostridium botulinum. Generally trivalent (abe) antitoxin is used. (12 Dec 1998) |
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| botulinum toxin | <protein> Neurotoxin (50 kD, 7 distinct serotypes) produced by certain strains of Clostridium botulinum. The bacterium produces the toxin as a complex with a haemagglutinin that prevents toxin inactivation in the gut. Proteolysis in the body results in cleavage into two fragments A and B. B binds to gangliosides and may stimulate the endocytosis of fragment A. See: synaptobrevin, tetanus toxin. (18 Nov 1997) |
| botulinum toxin type a | <chemical> A neurotoxin produced by clostridium botulinum. When consumed in contaminated food it can cause paralysis and death. In its purified form, it has been used in the treatment of blepharospasm and strabismus. Pharmacological action: neuromuscular agents. (12 Dec 1998) |
| botulinum toxins | <chemical> Toxins produced by clostridium botulinum. There are at least seven different substances, most being proteins. They have neuro-, entero-, and haemotoxic properties, are immunogenic, and include the most potent poisons known. The most commonly used apparently blocks release of acetylcholine at cholinergic synapses. Pharmacological action: anti-dyskinesia agents. (12 Dec 1998) |
| botulinus toxin | A potent neurotoxin from Clostridium botulinum. Synonym: botulin, botulismotoxin. (05 Mar 2000) |
| botulism | <disease, microbiology> An illness caused by a potent bacterial toxin (produced by Clostridium botulinum), this uncommon infection has four forms: infant botulism, food-borne botulism, wound botulism and botulism from an unknown source. (27 Sep 1997) |
| botulism antitoxin | Antitoxin specific for a toxin of one or another strain of Clostridium botulinum. Synonym: botulinum antitoxin. (05 Mar 2000) |
| botulism toxin | <protein> A toxic byproduct of Clostridium Botulinum that is responsible for the food-borne illness known as botulism. (27 Sep 1997) |
| botulismotoxin | A potent neurotoxin from Clostridium botulinum. Synonym: botulin, botulismotoxin. (05 Mar 2000) |
| botulogenic | Botulism-producing. Synonym: botulinogenic. (05 Mar 2000) |