| D-amino acid transferase | <enzyme> Mw 41 kD; catalyses d-amino acid transfer; d-configuration specific; recognises aromatic d-amino acid esters to form oligo d-amino acid esters Registry number: EC 2.3.2.- (26 Jun 1999) |
|---|---|
| dibasic amino acid | An amino acid containing a second basic group (usually an amino group); e.g., lysine, arginine, ornithine. Synonym: dibasic amino acid. (05 Mar 2000) |
| essential amino acid | <biochemistry> Those amino acids that cannot be synthesised by an organism and must therefore be present in the diet. The term is often applied anthropocentrically to those amino acids required by humans (Ileu, Leu, Lys, Met, Phe, Thr, Try, & Val), though rats need two more (Arg & His). (18 Nov 1997) |
| excitatory amino acid | <biochemistry> The naturally occurring amino acids L glutamate and L aspartate and their synthetic analogues, notably kainate, quisqualate and NMDA. They have the properties of excitatory neurotransmitters in the CNS, may be involved in long-term potentiation and can act as excitotoxins. at least three classes of EAA receptor have been identified, the agonists of the N type receptor are L aspartate, NMDA and ibotenate, the agonists of the Q type receptor are L glutamate and quisqualate, agonists of the K type are L glutamate and kainate. All three receptor types are found widely in the CNS and particularly the telencephalon, N and Q type receptors tend to occur together and may interact, their distribution is complementary to the K type receptors. The ion fluxes through the Q and K receptors are relatively brief, whereas the flux through the N type is longer and carries a significant amount of calcium. Additionally the N type receptor is blockaded by magnesium near the resting potential and thus shows voltage gated ion channel properties, leading to a regenerative response, this is why N type receptors have been linked to long-term potentiation. Invertebrate glutamate receptors may not have the same properties as those described above. (18 Nov 1997) |
| excitatory amino acid agents | Drugs used for their actions on any aspect of excitatory amino acid neurotransmitter systems. Included are drugs that act on excitatory amino acid receptors, affect the life cycle of excitatory amino acid transmitters, or affect the survival of neurons using excitatory amino acids. (12 Dec 1998) |
| excitatory amino acid agonists | Drugs that bind to and activate excitatory amino acid receptors. (12 Dec 1998) |
| excitatory amino acid antagonists | Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (12 Dec 1998) |
| 1-carbamoyl-L-amino acid amidohydrolase | <enzyme> From bacillus stearothermophilus; amino acid sequence given in first source Registry number: EC 3.5.1.- Synonym: carbamoyl l-aa amidohydrolase, n-carbamyl-l-amino acid amidohydrolase (26 Jun 1999) |
| 2-amino-2-deoxy-D-galactose | <chemical> Chemical name: D-Galactose, 2-amino-2-deoxy- (12 Dec 1998) |
| 2-amino-5-phosphonovalerate | <chemical> A potent and specific antagonist of nmda receptors (receptors, nmda) in the d-enantiomeric form. The l form is inactive at nmda receptors but may affect the ap4 (2-amino-4-phosphonobutyrate; apb) excitatory amino acid receptors. Pharmacological action: excitatory amino acid antagonists. Chemical name: Norvaline, 5-phosphono- (12 Dec 1998) |
| (3-(arginyl)amino-4-(4-nitrophenyl)butyryl)-leucyl-prolyl-threonine | Pharmacological action: neurotransmitters Synonym: 2-afb(p-no2)-proctolin, (afb(p-no2)(2))-proctolin (26 Jun 1999) |
| 8-amino-7-oxononanoate synthase | <enzyme> Chemical name: 7-keto-8-aminopelargonic acid synthetase Registry number: EC 2.3.1.47 Synonym: 7-kap synthetase, 8-amino-7-oxopelargonate synthase, 7-oxo-8-aminononanoate synthase, biof gene product (26 Jun 1999) |
| acids, carbocyclic | Carboxylic acids that have a homocyclic ring structure in which all the ring atoms are carbon. (12 Dec 1998) |
| acids, heterocyclic | A class of acids containing a ring structure in which atleast one atom other than carbon is incorporated. (12 Dec 1998) |
| acids, noncarboxylic | Inorganic acids with a non metal, other than carbon, attached to hydrogen, or an acid radical containing no carbon. (12 Dec 1998) |