| anaemia, haemolytic, congenital | Haemolytic anaemia due to various intrinsic defects of the erythrocyte. (12 Dec 1998) |
|---|---|
| anaemia, haemolytic, congenital nonspherocytic | Any one of a group of congenital haemolytic anaemias in which there is no abnormal haemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. In some cases, pyruvate kinase deficiency has been demonstrated; in other cases, glucose-6-phosphate dehydrogenase deficiency has been demonstrated. (12 Dec 1998) |
| anaemia, hypochromic | Anaemia characterised by a decrease in the ratio of the weight of haemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular haemoglobin concentration is less than normal. The individual cells contain less haemoglobin than they could have under optimal conditions. Hypochromic anaemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (12 Dec 1998) |
| anaemia, iron deficiency | Deficiency of iron results in anaemia because iron is necessary to make haemoglobin, the key molecule in red blood cells responsible for the transport of oxygen. In iron deficiency anaemia, the red cells are unusally small (microcytic) and pale (hypochromic). Characteristic features of iron deficiency anaemia in children include failure to thrive (grow) and increased infections. The treatment of iron deficiency anaemia, whether it be in children or adults, is with iron and iron-containing foods. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. Anaemia characterised by low or absent iron stores, low serum iron concentration, elevated free erythrocyte porphorin, low transferrin saturation, elevated transferrin, low serum ferritin, low haemoglobin concentration or haematocrit, and hypochromic microcytic red blood cells. Symptoms may include pallor, angular stomatitis and other oral lesions, gastrointestinal complaints, retinal haemorrhages and exudates, and thinning and brittleness of the nails. Among the causes of iron-deficiency anaemia are inadequate iron intake, impaired iron absorption, increased blood loss and increased requirements such as infancy, pregnancy, and lactation. (12 Dec 1998) |
| anaemia, macrocytic | Anaemia characterised by larger than normal erythrocytes, increased mean corpuscular volume (mcv) and increased mean corpuscular haemoglobin (mch). (12 Dec 1998) |
| anaemia, mediterranean | Better known today as thalassaemia (or as beta thalassaemia or thalassaemia major).The clinical picture of this important type of anaemia was first described in 1925 by the paediatrician Thomas Benton Cooley. The name thalassaemia was coined by the Nobel Prise winning pathologist George Whipple and the professor of paediatrics Wm Bradford at U. Of Rochester because thalassa in Greek means the sea (like the Mediterrranean Sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of Mediterranean origin (for example, from Italy and Greece). Children with this disease inherit one gene for it from each parent. The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth because at birth we still have predominantly foetal haemoglobin which does not contain beta chains. The anaemia surfaces in the first few months after birth and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease. (12 Dec 1998) |
| anaemia, megaloblastic | Anaemia characterised by the presence of megaloblasts in the bone marrow. (12 Dec 1998) |
| anaemia, myelophthisic | Anaemia characterised by appearance of immature myeloid and nucleated erythrocytes in the peripheral blood, resulting from infiltration of the bone marrow by foreign or abnormal tissue. (12 Dec 1998) |
| anaemia, neonatal | The mildest form of erythroblastosis foetalis in which anaemia is the chief manifestation. (12 Dec 1998) |
| anaemia, pernicious | A megaloblastic anaemia occurring in children but more commonly in later life, characterised by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin b 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (12 Dec 1998) |
| anaemia, refractory | Anaemia (a shortage of red blood cells) unresponsive to treatment. (12 Dec 1998) |
| anaemia, refractory, with excess of blasts | Chronic refractory anaemia with granulocytopenia, and/or thrombocytopenia. Myeloblasts and progranulocytes constitute 5 to 40 percent of the nucleated marrow cells. (12 Dec 1998) |
| anaemia, sickle cell | A disease characterised by chronic haemolytic anaemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for haemoglobin s. (12 Dec 1998) |
| anaemia, sideroblastic | Anaemia characterised by the presence of erythroblasts containing excessive deposits of iron in the marrow. (12 Dec 1998) |
| anaemic | Pertaining to or manifesting the various features of anaemia. (05 Mar 2000) |
Synonyms : Analgesic Agents, Analgesic Drugs, Agents, Analgesic, Drugs, Analgesic
Synonyms : Analgesics, Nonnarcotic, Analgesics, Nonopioid, Analgesics, Non Narcotic, Non-Narcotic Analgesics, Nonnarcotic Analgesics
Synonyms :
Synonyms : Analogue-Digital Conversion, Analog Digital Conversion, Analog-Digital Conversions, Analogue Digital Conversion, Analogue-Digital Conversions, Conversion, Analog-Digital, Conversion, Analogue-Digital, Conversions, Analog-Digital, Conversions, Analogue-Digital
Synonyms : Analysis, Variance, Variance Analysis, Analyses, Variance, Variance Analyses
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| analysis of variance |
a statistical method for making simultaneous comparisons between two or more means; a statistical method that yields values that can be tested to determine whether a significant relation exists between variables
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| anastigmatic |
pertaining to a lens or lens system free of astigmatism (able to form point images) not astigmatic
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| anastigmatic lens |
a lens designed to correct astigmatism
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| analyst |
someone who is skilled at analyzing data an expert who studies financial data (on credit or securities or sales or financial patterns etc.) and recommends appropriate business actions a licensed practitioner of psychoanalysis
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| anadromous |
migrating from the sea to fresh water to spawn
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| ANA | exercise that builds muscles through tension |
|---|---|
| ANA | living or active in the absence of free oxygen |
| ANA | loss of bodily sensation with or without loss of consciousness |
| ANA | a drug that causes temporary loss of bodily sensations |
| ANA | characterized by insensibility |
| ANA | a drug that causes temporary loss of bodily sensations |
| ANA | make unconscious by means of anesthetic drugs |
| ANA | rendered insensible by means of anesthesia |
| ANA | a specialist who administers an anesthetic to a patient before he is treated |
| ANA | make unconscious by means of anesthetic drugs |
| ANA | rendered insensible by means of anesthesia |
| ANA | chiefly Old World herbs |
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