| Gm antigens | Allotypic determinants (antigens) that are present on the heavy chain of immunoglobulin G. There are 25 different determinants present throughout the human population. (05 Mar 2000) |
|---|---|
| Rh antigens | rh blood group |
| group antigens | Antigen's that are shared by related genera of microorganisms. (05 Mar 2000) |
| class I antigens | Cell membrane bound glycoproteins that are coded by genes of the major histocompatibility complex. (05 Mar 2000) |
| class II antigens | A cell membrane glycoprotein encoded by genes of the major histocompatibility complex. These antigens are distributed on antigen-presenting cells such as macrophages, B-cells, and dendritic cells. (05 Mar 2000) |
| class III antigens | Non-cell membrane molecules that are encoded by the S region of the major histocompatibility complex. These antigens are not involved in determining histocompatibility and include the complement proteins. (05 Mar 2000) |
| minor histocompatibility antigens | Allelic alloantigens often responsible for weak graft rejection in cases when (major) histocompatibility has been established by standard tests. In the mouse they are coded by more than 500 genes at up to 30 minor histocompatibility loci. The most well-known minor histocompatibility antigen in mammals is the h-y antigen. (12 Dec 1998) |
| minor lymphocyte stimulatory antigens | Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see mixed lymphocyte culture test). They are encoded by mouse mammary tumour viruses that have integrated into the germ line as DNA proviruses (minor lymphocyte stimulatory loci). (12 Dec 1998) |
| MN blood group antigens | <haematology, immunology> A pair of blood group antigens governed by genes that segregate independently of the ABO locus. The alleles are codominant and there are three types MM, NN and MN. Glycophorin has M or N activity and this is associated with oligosaccharides attached to the amino terminal portion of the molecule. M type glycophorin differs from N type in amino acid residues 1 and 5, although the antigenic determinants are associated with the carbohydrate side chains. (18 Nov 1997) |
| hepatitis antigens | Antigens from any of the hepatitis viruses including surface, core, and other associated antigens. (12 Dec 1998) |
| hepatitis b e antigens | A closely related group of antigens found in the plasma only during the infective phase of hepatitis b or in virulent chronic hepatitis b, probably indicating active virus replication; there are three subtypes which may exist in a complex with immunoglobulins g. (12 Dec 1998) |
| hepatitis b surface antigens | Those hepatitis b antigens found on the surface of the dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen. (12 Dec 1998) |
| hepatitis c antigens | Antigens of the virions of hepatitis c-like viruses, their surface, core, or other associated antigens. (12 Dec 1998) |
| histocompatibility antigens | A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection. (12 Dec 1998) |
| histocompatibility antigens class I | Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-a, HLA-b and HLA-c antigens. In mice, three genes named k, d, and l on chromosome 17 code for the h-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognised during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders. (12 Dec 1998) |