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2-aminopurine <chemical> A purine that is an isomer of adenine (6-aminopurine).
Pharmacological action: antimetabolites.
Chemical name: 1H-Purin-2-amine
(12 Dec 1998)
2-arylpropionyl-CoA epimerase <enzyme> From rat liver cytosol and mitochondria; catalyses a rapid interconversion between the r- and s-epimers of 2-arylpropionic acids which upon the action of a thioesterase on the r-isomer yields the free acid
Registry number: EC 5.1.99.-
(26 Jun 1999)
2-carboxyarabinitol 1-phosphate phosphatase <enzyme> Catalyses 2-carboxyarabinitol 1-phosphate into 2-carboxyarabinitol and inorganic phosphate; from leaves of french bean, phaseolus vulgaris
Registry number: EC 3.1.3.-
Synonym: ca1p phosphatase, ca1pase
(26 Jun 1999)
2-carboxybenzaldehyde dehydrogenase <enzyme> Catalyses conversion of 2-carboxybenzaldehyde to o-phthalic acid in the phenanthrene degradation pathway; isolated from nocardioides; genbank ab000735
Registry number: EC 1.2.1.-
Synonym: phdk gene product
(26 Jun 1999)
2-chloroadenosine <chemical> 2-chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system.
Chemical name: Adenosine, 2-chloro-
(12 Dec 1998)
2-dehydro-3-deoxyphosphoheptonate aldolase <enzyme> An enzyme that catalyses the formation of 7-phospho-2-keto-3-deoxy-d-arabinoheptonate from phosphoenolpyruvate and d-erythrose-4-phosphate. It is one of the first enzymes in the biosynthesis of tyrosine and phenylalanine.
Chemical name: 2-Dehydro-3-deoxy-D-arabino-heptonate-7-phosphate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)
Registry number: EC 4.1.2.15
(12 Dec 1998)
2-dehydro-3-deoxyphosphooctonate aldolase <enzyme> Arabinose-5-phosphate + phosphoenolypyruvate yields kdo-8p-p; may be the same as EC 4.1.2.23 which has unphosphorylated substrates; genbank z50747
Registry number: EC 4.1.2.16
Synonym: 2-keto-3-deoxyoctonate-8-phosphate synthetase, 2-kdop-synthetase, kdo 8-phosphate synthase, 3-deoxy-d-manno-octulosonic acid-8-phosphate synthetase, kdo-8-phosphate synthetase, kdsa gene product
(26 Jun 1999)
2-deoxy-scyllo-inosose synthase <enzyme> Responsible for the formation of 2-deoxy-scyllo-inosose from d-glucose; exhibits close similarity to dehydroquinate synthase; not clear whether it catalyses only the oxidoreduction of c-4 and/or the intramolecular cyclization between c-1 and c-6
Registry number: EC 4.99.-
Synonym: 2-deoxy-scyllo-inosose synthetase
(26 Jun 1999)
2-deoxycoformycin <chemical> A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukaemia. It is also synergistic with some other antineoplastic agent and has immunosuppressive activity.
Pharmacological action: antibiotics, antineoplastic, enzyme inhibitors, immunosuppressive agents.
Chemical name: Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-
(12 Dec 1998)
2-deoxyglucose-6-phosphate phosphatase <enzyme> Prevents intracellular accumulation of 2-deoxyglucose-6-phosphate; from saccharomyces cerevisiae; genbank u03107
Registry number: EC 3.1.3.-
Synonym: dog-6-p phosphatase, dog(r)1 protein, dog(r)1 gene product
(26 Jun 1999)
2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase <enzyme> From rhodobacter capsulatus; catalyses the penultimate step in bacteriochlorophyll a biosynthesis
Registry number: EC 1.-
Synonym: bchc gene product, bchc bacteriochlorophyll biosynthesis gene product
(26 Jun 1999)
2-enoate reductase <enzyme> Am iron-sulfur flavoprotein which reduces alpha,beta-unsaturated carboxylate anions in a NADPH-dependent reaction to saturated carboxylated anions
Registry number: EC 1.3.1.31
(26 Jun 1999)
2-enoyl-CoA reductase Acyl-CoA dehydrogenase (NADP+).
(05 Mar 2000)
2-furoyl-CoA dehydrogenase <enzyme> Chemical name: 2-furoyl-CoA hydroxylase
Registry number: EC 1.3.99.8
Synonym: 2-furoyl-coenzyme a dehydrogenase
(26 Jun 1999)
2-haloacid dehalogenase <enzyme> Catalyses hydrolysis of 2-haloacid to hydroxyacid and halide; enzyme from psuedomonas alcaligenes acts on 2-chloropropionate, 2,2-dichloropropionate, 2-chloroacetate and 2,2-dichloroacetate; dhlb gene is in xanthobacter autotrophicus
Registry number: EC 3.8.1.2
Synonym: 2-chloropropionate dehalogenase, 2-haloalkanoic acid dehalogenase, dehi dehalogenase, dehii dehalogenase, 2-haloacid halidohydrolase iva, 2,2-dichloropropionate dehalogenase, haloacid dehalogenase, dhlb gene product, dehl gene product, dehd gene product
(26 Jun 1999)
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