| FAT | family attitudes test; fluorescent antibody technique; fluorescent antibody test |
|---|---|
| FTA | fluorescent titer antibody; fluorescent treponemal antibody |
| HA | H antigen; Hakim-Adams [syndrome]; halothane anesthesia; Hartley [guinea pig]; headache; health alli... |
| IFA | idiopathic fibrosing alveolitis; immunofluorescence assay; immunofluorescent antibody; incomplete Fr... |
| MA | malignant arrhythmia; management and administration; mandelic acid; masseter; Master of Arts; matern... |
| maternal antibody | Any antibody transferred from a mammalian mother transplacentally into the foetus. See under immunoglobulin for details of the classes of Ig that are transferred to the foetus. (18 Nov 1997) |
|---|---|
| catalytic antibody | <chemistry> Antibody raised against a transition state analogue (e.g. A phosphate analogue of a carboxylic acid ester transition state) that can then catalyse the analogous chemical reaction, though not as effectively as a true enzyme. (16 Mar 1998) |
| Vi antibody | A form of antibody that agglutinates highly virulent strains of Salmonella typhi, i.e., cells with Vi antigen; such bacteria are not agglutinable with O antiserum until the Vi antigen is destroyed. See: Vi antigen. (05 Mar 2000) |
| cell-bound antibody | A term used for antibody on the surface of cells that may be bound either through antigen combining sites or other sites such as the Fc region. (05 Mar 2000) |
| CF antibody | Antibody that combines with and sensitises antigen leading to the activation of complement, which may result in cell lysis. Synonym: CF antibody, sensitizing substance. (05 Mar 2000) |
| chimeric antibody | <immunology> An antibody that contains polypeptides from different species. (05 Jan 1998) |
| chimeric/humanised antibody | <immunology> Genetically engineered combination of a human and mouse antibody. Because a monoclonal antibody is always made with mice cells, it causes an immune response when injected into humans. By replacing the constant regions of a mouse antibody with those of a human antibody, an antibody that binds to an antigen like the original monoclonal antibody, but which is recognised by the human immune system like a human protein, can be manufactured. Alternatively, only those amino acids directly involved in antigen binding are transferred from the mouse antibody into the framework of the human antibody, with a similar result. (05 Jan 1998) |
| microsomal antibody | This special serologic test is used to measure thyroid anti-microsomal antibody in the bloodstream. This test can be performed from a simple venipuncture specimen. The anti-microsomal antibody or microsomal antibody test is used to diagnose conditions such as Hashimoto's thyroiditis and other autoimmune disorders. (27 Sep 1997) |
| Wassermann antibody | Antibody, evoked during syphilitic infections, that combines with cardiolipin in the presence of lecithin and cholesterol; it is distinct from the treponema-immobilizing antibody. (05 Mar 2000) |
| cold antibody | See: cold agglutinin. (05 Mar 2000) |
| cold-reactive antibody | See: cold agglutinin. (05 Mar 2000) |
| monoclonal antibody | <immunology, molecular biology> A substance, usually a protein, which can be synthsised in the laboratory in pure form by a single clone (population) of cells. These antibodies can be made in large quantities and have a specific affinity for certain target molecules called antigens which can be found on the surface of cells and those that are malignant. Monoclonal antibodies are currently being investigated as a possible form of cancer treatment although their benefit has not be fully proven. (16 Dec 1997) |
| complement-fixing antibody | Antibody that combines with and sensitises antigen leading to the activation of complement, which may result in cell lysis. Synonym: CF antibody, sensitizing substance. (05 Mar 2000) |
| complete antibody | An antibody which causes agglutination of erythrocytes when they are suspended either in saline or in a protein medium. (05 Mar 2000) |
| polyclonal antibody | An antibody produced by several clones of B lymphocytes as would be the case in a whole animal. Usually refers to antibodies raised in immunised animals, whereas a monoclonal antibody is the product of a single clone of B lymphocytes, usually maintained in vitro. (18 Nov 1997) |