| receptor tyrosine kinase | Class of membrane receptors that phosphorylate tyrosine residues. Many play significant roles in development or cell division. Examples: insulin receptor family, c ros receptor, Drosophila sevenless, trk family. (18 Nov 1997) |
|---|---|
| Cek4 receptor protein-tyrosine kinase | <enzyme> Isolated from mouse and chicken. Registry number: EC 2.7.1.- Synonym: cek4 protein, cek4 eph receptor, eph receptor cek4 (26 Jun 1999) |
| megakaryocyte-associated tyrosine kinase | <enzyme> Genbank l18974 Registry number: EC 2.7.1.- Synonym: matk protein, csk homologous kinase, chk enzyme (26 Jun 1999) |
| PEP protein tyrosine phosphatase | <enzyme> Pest - pro, glu, ser and thr; an intracellular ptpase expressed primarily by cells of haematopoietic origin; involved in regulating nuclear tyrosine phosphorylation; amino acid sequence has been determined Registry number: EC 3.1.3.- Synonym: pep ptpase, pest-enriched phosphatase, ptp-pest (26 Jun 1999) |
| RNA-tyrosine phosphatase | <enzyme> Hela cell enzyme which removes 5'-terminal protein from poliovirus RNA by breaking the tyrosine-phosphate bond between the above two entities Registry number: EC 3.1.4.- Synonym: uridylyl-(5'p-o)-tyrosine phosphodiesterase, y-pupnpde, tyrosine-RNA phosphatase, uridylylpolynucleotide-(5'p-o)-tyrosine phosphodiesterase (26 Jun 1999) |
| PL7a receptor-tyrosine kinase | <enzyme> A member of the eph receptor tyrosine kinase subfamily; shows 80% identity with myk-1; genbank l43622 Registry number: EC 2.7.1.- Synonym: pl7a protein (26 Jun 1999) |
| H1-related protein-tyrosine phosphatase | <enzyme> Has tyrosine and threonine/serine phosphatase activities Registry number: EC 3.1.3.- Synonym: vaccinia virus h1-related protein tyrosine phosphatase, vhr ptpase, vh-ptp13 (26 Jun 1999) |
| Csk-like protein-tyrosine kinase | <enzyme> Phosphorylates c-terminal conserved tyr of src family members; from mouse brain; has 52% identity with mouse csk; mw 52 kD; genbank u05210 Registry number: EC 2.7.1.- Synonym: ctk (kinase), ctk gene product, csk-type protein-tyrosine kinase, ntk (kinase), bhk (kinase) (26 Jun 1999) |
| protein-tyrosine kinase | <enzyme> An enzyme that catalyses the phosphorylation of tyrosine residues in proteins with ATP or other nucleotides as phosphate donors.12. Chemical name: ATP:protein-tyrosine O-phosphotransferase Registry number: EC 2.7.1.112 (12 Dec 1998) |
| protein-tyrosine-phosphatase | <enzyme> An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with protein-tyrosine kinase, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. Chemical name: Protein-tyrosine-phosphate phosphohydrolase Registry number: EC 3.1.3.48 (12 Dec 1998) |
| pyp2 protein tyrosine phosphatase | <enzyme> Shares an essential overlapping role with pyp1 ptpase and is 42% identical in sequence in the c-terminal catalytic domain of pyp1; involved in negative regulation of mitosis in fission yeast Registry number: EC 3.1.3.- Synonym: pyp2 ptpase, pyp2 gene product (26 Jun 1999) |
| pyp3 protein tyrosine phosphatase | <enzyme> Acts as mitotic inducer in fission yeast Registry number: EC 3.1.3.- Synonym: pyp3 gene product, pyp3 ptpase (26 Jun 1999) |
| SH protein-tyrosine phosphatase | <enzyme> Has sequence similarity to src-homology region 2 Registry number: EC 3.1.3.- Synonym: sh-ptp3, sh-ptp1, ptp1c, protein-tyrosine-phosphatase 1c, protein tyrosine phosphatase, nonreceptor type 6, ptpn6, shptp1, protein-tyrosine phosphatase shp, shp ptpase, shp-1, shp-2 (26 Jun 1999) |
| stomach cancer-associated protein-tyrosine phosphatase | <enzyme> Human transmembrane-type ptpase expressed in gastric, pancreatic and colourectal cancer cells; consists of 1093 amino acid; mw 200 kD; genbank d15049 Registry number: EC 3.1.3.- Synonym: sap 1 phosphatase (26 Jun 1999) |
| nonreceptor protein tyrosine kinase | <enzyme> Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (18 Nov 1997) |