| class III antigens | Non-cell membrane molecules that are encoded by the S region of the major histocompatibility complex. These antigens are not involved in determining histocompatibility and include the complement proteins. (05 Mar 2000) |
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| class III malocclusion | <dentistry> A Malocclusion where your lower teeth stick out past your upper teeth. This is also called an underbite. (05 Mar 2000) |
| clinical trial, phase III | A pre-planned, usually controlled, clinical study of the safety and efficacy of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques after phase II trials. A large enough group of patients is studied and closely monitored by physicians for adverse response to long-term exposure, over a period of about three years in either the united states or a foreign country. (12 Dec 1998) |
| clinical trials, phase III | Comparative studies to verify the effectiveness of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques determined in phase II studies. During these trials, patients are monitored closely by physicians to identify any adverse reactions from long-term use. These studies are performed on groups of patients large enough to identify clinically significant responses and usually last about three years. This concept includes phase III studies conducted in both the u.s. And in other countries. (12 Dec 1998) |
| mucolipidosis III | <biochemistry> Mucolipidosis with mild Hurler-like symptoms, restricted joint mobility, short stature, mild mental retardation, and dysplastic skeletal changes, especially of the hip. Aortic and mitral valve disease are often present. It is associated with a deficiency of UDP-N-acetyl glucosamine and lysosomal enzyme N-acetylglucosaminyl-1-phosphotransferase. Inheritance: autosomal recessive. Synonym: pseudo-Hurler polydystrophy, pseudopolydystrophy. (05 Mar 2000) |
| congenital antithrombin III deficiency | Antithrombin III is a protein which stimulates the removal of blood clots in the bloodstream. Small blood clots form normally within the bloodstream, but are normally dissolved via the bodys antithrombin III. The deficiency of antithrombin III will result in an increased risk for blood clot formation causing organ damage. This is an inherited as a autosomal dominant trait. Inheritance: autosomal dominant. (27 Sep 1997) |
| connective tissue activating peptide III | Cytokine, produced from platelet basic protein, that acts as a growth factor. (18 Nov 1997) |
| mycinamicin III O-methyltransferase | <enzyme> Catalyses the incorporation of the methyl group of s-adenosyl-l-methionine at the 3'' position of mycinamicin III; from micromonospora griseorubida; genbank d16097 Registry number: EC 2.1.1.- Synonym: mycf gene product, miii o-mtase (26 Jun 1999) |
| cranial mononeuropathy III | (compression type) A disorder involving vision changes and eyelid drooping associated with a decreased functioning of cranial nerve III. Damage is usually caused by compression of the nerves from localised lesions or a swelling in the area of the nerve. Examples include cerebral aneurysms and tumours Symptoms include a drooping eyelid and double vision. (diabetic type) A disorder involving vision changes and eyelid drooping associated with a decreased functioning of cranial nerve III as a complication of diabetes. Symptoms include a drooping eyelid and double vision. Good control of blood sugars can reduce the incidence of this complication. (27 Sep 1997) |
| cranial nerve III | <anatomy, nerve> The occulomotor nerve is responsible for motor enervation of upper eyelid muscle, extraocular muscle and pupillary muscle. Lesions of the oculomotor nerve results in ptosis (dropping eyelid), deviation of the eyeball outward, double vision and a dilated pupil. Synonym: cranial nerve III. (27 Sep 1997) |
| processus styloideus ossis metacarpalis III | A pointed projection from the dorsolateral angle of the base of the third metacarpal bone; it sometimes exists as a separate ossicle. Synonym: processus styloideus ossis metacarpalis III. (05 Mar 2000) |
| Hind III | <enzyme, molecular biology> Commonly used type II restriction endonuclease isolated from Haemophilus influenzae, it cleaves the sequence AAGCTT between the two As thus generating sticky ends. (18 Nov 1997) |
| HTLV-III | <abbreviation> Human T-cell lymphotropic virus type III. See: human immunodeficiency virus. (05 Mar 2000) |
| NADH-Fe(III)EDTA oxidoreductase | <enzyme> From cryptococcus albidus; catalyses the formation of nad+ and fe(ii)edta from NADH and fe(iii)edta; forms ethylene from 2-oxo-4-methylthiobutyric acid Registry number: EC 1.6.99.- (26 Jun 1999) |
| Sudan III | A red stain, (C6H5)N==N(C6H4)N==N(C10H6)OH, used for neutral fat in histologic technique; it also stains the fatty envelope of the tubercle bacillus. Synonym: Sudan red III. (05 Mar 2000) |