| trypanocide |
an agent that kills trypanosomes; called also trypanosomicide.
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| trypanolytic |
pertaining to or causing trypanolysis. Cf. trypanocidal.
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| Trypanosoma |
a genus of protozoa (suborder Trypanosomatina, order Kinetoplastida) comprising hemoflagellates parasitic in invertebrates and vertebrates, including humans; several species are pathogenic. Their life cycle involves amastigote, promastigote, epimastigote, and trypomastigote stages; the first three stages are found in the vector (usually a bloodsucking invertebrate) and the last in the vertebrate (definitive) host. In some systems of classification, trypanosomes are categorized in two groups according to where they develop in the digestive system of the vector: salivaria, including the subgenera Duttonella, Nannomonas, and Trypanozoon; and stercoraria, including the subgenera Megatrypanum, Herpetosoma, and Schizotrypanum. Another system classifies them into four groups based on biological similarities: (1) lewisi group, including T. lewisi, T. duttoni, T. theileri, T. cruzi, T. nabiasi, T. melophagium, and T. rangeli; (2) vivax group, including T. vivax and T. uniforme; (3) congolense group, including T. congolense, T. dimorphon, and T. simiae; and (4) brucei group, including T. brucei, T. gambiense, T. rhodesiense, T. evansi, T. equinum, and T. equiperdum.
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| trypanosomatid |
1. any protozoan of the suborder Trypanosomatina. 2. pertaining to or caused by a protozoan of the suborder Trypanosomatina.
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| Trypanosomatina |
a suborder of parasitic protozoa (order Kinetoplastida, class Zoomastigophorea) comprising the hemoflagellates, which are found in the hosts' blood, lymph, and tissues, and are characterized by a leaflike or rounded body with one nucleus, one flagellum that is free or attached to the body by an undulating membrane, and a relatively small compact kinetoplast. All trypanosomatids have morphologically distinct stages in their life cycles during which the organisms of one genus may pass through forms characteristic of other genera of the suborder. These forms include: amastigote, choanomastigote, epimastigote, opisthomastigote, promastigote, and trypomastigote. Not all species pass through all of the stages, but all have at least two such forms during their development. Representative genera include Blastocrithidia, Crithidia, Leishmania, Leptomonas, and Trypanosoma.
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