| Ki-1+ lymphoma | <tumour> A form of lymphoma characterised by anaplasia of cells, sinusoidal growth, and immunoreactivity with CD30 (Ki-1 or Ber-H2). Synonym: Ki-1+ lymphoma. (05 Mar 2000) |
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| follicular lymphoma | <tumour> A malignant lymphoma arising from lymphoid follicular B-cells which may be small or large, growing in a nodular pattern. Synonym: follicular lymphoma, giant follicular lymphoblastoma. (05 Mar 2000) |
| Lennert's lymphoma | <tumour> Malignant lymphoma with a high proportion of diffusely scattered epithelioid cells, tonsillar involvement, and an unpredictable course. Synonym: Lennert's lesion. (05 Mar 2000) |
| lymphoblastic lymphoma | <tumour> A diffuse lymphoma in children, with supradiaphragmatic distribution and T lymphocytes having convoluted nuclei; many patients develop acute lymphoblastic leukaemia. (05 Mar 2000) |
| lymphocytic lymphoma | <oncology, tumour> A cancer of lymphatic tissues, the tumour cells are mostly abnormal lymphocytes. (13 Nov 1997) |
| lymphoma | <oncology, tumour> Malignant tumour of lymphoblasts derived from B lymphocytes. most commonly affects children in tropical Africa: both Epstein Barr virus and immunosuppression due to malarial infection are involved. (18 Nov 1997) |
| lymphoma, aids-related | B-cell lymphoid tumours that occur in association with aids. Patients often present with an advanced stage of disease and highly malignant subtypes including burkitt lymphoma, immunoblastic large-cell lymphoma, small non-cleaved-cell lymphoma and diffuse large-cell lymphoma. The tumours are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in aids is a complex result of ebv infection, HIV antigenic stimulation, and T-cell-dependent HIV activation. (12 Dec 1998) |
| lymphoma, diffuse | Malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organised pattern. Patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern. (12 Dec 1998) |
| lymphoma, follicular | Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centres of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular centre B-lymphocytes. This class of lymphoma usually occurs in older persons, is commonly multinodal, and possibly extranodal. Patients whose lymphomas present a follicular or nodular pattern generally have a more indolent course than those presenting with a diffuse pattern. (12 Dec 1998) |
| lymphoma, high-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively unfavorable survival potential. (12 Dec 1998) |
| lymphoma, intermediate-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have an intermediate survival potential. (12 Dec 1998) |
| lymphoma, low-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively favourable survival potential. (12 Dec 1998) |
| lymphoma, lymphoblastic | A high-grade malignant lymphoma composed of a diffuse, relatively uniform proliferation of cells with round or convoluted nuclei and scanty cytoplasm. The cells are cytologically similar to the lymphoblasts seen in acute lymphocytic leukaemia, and in some cases, the disease may evolve into a leukaemic phase morphologically indistinguishable from acute t-lymphocytic leukaemia (leukaemia, T-cell, acute). Lymphoblastic lymphoma represents approximately one-third of the cases of non-hodgkin's lymphomas in children and 5% of the cases in adults. It is more prevalent in males. (12 Dec 1998) |
| lymphoma, mucosa-associated lymphoid tissue | Extranodal lymphoma of lymphoid tissue associated with mucosa that is in contact with exogenous antigens. Many of the sites of these lymphomas, such as the stomach, salivary gland, and thyroid, are normally devoid of lymphoid tissue. They acquire malt tissue as a result of an immunologically mediated disorder. (12 Dec 1998) |
| lymphoma, non-hodgkin | Any of a group of malignant tumours of lymphoid tissue that differ from hodgkin disease, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumours is the absence of giant reed-sternberg cells, a characteristic of hodgkin's disease. (12 Dec 1998) |