| dose-response relationship, drug | The relationship between the dose of an administered drug and the response of the organism to the drug. (12 Dec 1998) |
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| dose-response relationship, immunologic | A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell. (12 Dec 1998) |
| dose-response relationship, radiation | The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation. (12 Dec 1998) |
| immune response | <immunology> Alteration in the reactivity of an organisms immune system in response to an antigen, in vertebrates, this may involve antibody production, induction of cell-mediated immunity, complement activation or development of immunological tolerance. (18 Nov 1997) |
| immune-response gene | <molecular biology> Any of several genes of the major histocompatibility complex that control the immune response of lymphocytes to specific antigens. (09 Oct 1997) |
| immune response genes | Gene's in the HLA-D region of the histocompatibility complex of human chromosome 6 which control the immune response to specific antigens. (05 Mar 2000) |
| inflammatory response | A part of innate immunity. Inflammation occurs when tissues are injured by viruses, bacteria, trauma, chemicals, heat, cold or any other harmful stimulus. Chemicals including bradykinin, histamine, serotonin and others are released by specialised cells. These chemicals attract tissue macrophages and white blood cells to localise in an area to engulf (phagocytize) and destroy foreign substances. A byproduct of this activity is the formation of pus--a combination of white blood cells, bacteria and foreign debris. The chemical mediators released during the inflammatory response give rise to the typical findings associated with inflammation. (27 Sep 1997) |
| isomorphic response | An isomorphic reaction seen in response to trauma in previously uninvolved sites of patients with skin diseases including psoriasis and lichen planus, typically with lesions in a linear pattern at sites of scratching or a scar. Synonym: isomorphic response. (05 Mar 2000) |
| oculomotor response | Widespread myogenic potential evoked by visual stimuli. (05 Mar 2000) |
| orienting response | An aspect of attending in which an organism's initial response to a change or to a novel stimulus is such that the organism becomes more sensitive to the stimulation; e.g., dilation of the pupil of the eye in response to dim light. Synonym: investigatory reflex, orienting response. (05 Mar 2000) |
| overall response rate | <pharmacology> Sum of complete and partial tumour responses seen in a study, divided by the number of evaluable patients. (05 Jan 1998) |
| target response | In conditioning, any behaviour or specific response chosen by the experimenter; its frequency is intended to increase or decrease by the judicious pairing with it of a reinforcer when it occurs. Synonym: target behaviour, target response. (05 Mar 2000) |
| th1 response | <immunology> An acquired immune response whose most prominent feature is high cytotoxic T lymphocyte activity relative to the amount of antibody production. The Th1 response is promoted by CD4+ Th1 T-helper cells. See: Th2 Response. (09 Oct 1997) |
| th2 response | <immunology> An acquired immune response whose most prominent feature is high antibody production relative to the amount of cytotoxic T lymphocyte activity The Th2 response is promoted by CD4+ Th2 T-helper cells. See: TO Response. (09 Oct 1997) |
| early-phase response | Prompt onset of symptoms following an antigenic stimulus. (05 Mar 2000) |