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staphylococcal scalded skin s. an infectious disease of infants, young children, and occasionally older children and adults, seen after infection with certain strains of Staphylococcus aureus (phage group II), which elaborate exfoliatin (q.v.), an epidermolytic erythrogen endotoxin. Clinical signs range from a localized bulla to widespread fine vesicles and bullae that are easily ruptured, resulting in exfoliation of large sheets of skin, leaving raw, denuded areas that make the skin surface look scalded. Called also dermatitis exfoliativa neonatorum and Ritter's disease. Cf. toxic epidermal necrolysis.
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staphylococcal t. a mixture of exotoxins produced by Staphylococcus aureus. There are four chemically and serologically distinct hemolysins (α, β, γ, and δ) having also dermonecrotic activity (α-hemolysin), sphingomyelinase activity (β-hemolysin), necrotizing activity (γ-hemolysin), and leukocidin activity (δ-hemolysin). Other toxins produced are leukocytal and exfoliative (causing scalded skin syndrome). Strains of S. aureus also produce five serologically distinct enterotoxins: types A and D are major factors in staphylococcal food poisoning.
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staphylococcemia a condition in which staphylococci are present in the blood; septicemia caused by staphylococci.
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staphylococcic staphylococcal.
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staphylococcin a bacteriocin produced by certain strains of Staphylococcus aureus.
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