| receptors, cholinergic | Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behaviour of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology. (12 Dec 1998) |
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| receptors, colony-stimulating factor | Cell surface receptors for colony-stimulating factors, local mediators, and hormones that regulate the survival, proliferation, and differentiation of haemopoietic cells. (12 Dec 1998) |
| receptors, complement | Molecules on the surface of some B-lymphocytes and macrophages, that recognise and combine with the c3b, c3d, c1q, and c4b components of complement. (12 Dec 1998) |
| receptors, complement 3b | Molecular sites on or in some B-lymphocytes and macrophages that recognise and combine with complement 3b. The primary structure of these receptors reveal that they contain transmembrane and cytoplasmic domains, with their extracellular portion composed entirely of thirty short consensus repeats each having 60 to 70 amino acids. (12 Dec 1998) |
| receptors, complement 3d | Molecular sites on or in B-lymphocytes, follicular dendritic cells, lymphoid cells, and epithelial cells that recognise and combine with complement 3d. Human cr2 serves as a receptor for both c3dg and the gp350/220 glycoprotein of herpes virus 4, human, and binds the monoclonal antibody okb7, which blocks binding of both ligands to the receptor. (12 Dec 1998) |
| receptors, concanavalin a | Glycoprotein moieties on the surfaces of cell membranes that bind concanavalin a selectively; the number and location of the sites depends on the type and condition of the cell. (12 Dec 1998) |
| receptors, corticotropin | Cell surface receptors that bind corticotropin (acth, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple acth receptors. An acth receptor has been cloned and belongs to a subfamily of g-protein-coupled receptors. In addition to the adrenal cortex, acth receptors are found in the brain and immune systems. (12 Dec 1998) |
| receptors, corticotropin-releasing hormone | Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behaviour of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood. (12 Dec 1998) |
| receptors, cxcr4 | Seven-transmembrane G-protein-coupled receptors for alpha-chemokines. They also function as fusion cofactors for T-cell-tropic HIV-1 strains. (12 Dec 1998) |
| receptors, cyclic AMP | Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behaviour of cells. The best characterised cyclic AMP receptors are those of the slime mold dictyostelium discoideum. The transcription regulator cyclic AMP receptor protein of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| receptors, cytoadhesin | A group of integrins that includes the platelet outer membrane glycoprotein gpiib-iiia (platelet glycoprotein gpiib-iiia complex) and the vitronectin receptor (receptors, vitronectin). They play a major role in cell adhesion and serve as receptors for fibronectin, von willebrand factor, and vitronectin. (12 Dec 1998) |
| receptors, cytokine | Cell surface proteins that bind cytokines and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
| receptors, cytoplasmic and nuclear | Proteins in the cytoplasm or nucleus that specifically bind signalling molecules and trigger changes which influence the behaviour of cells. The major groups are the steroid hormone receptors, which usually are found in the cytoplasm, and the thyroid hormone receptors, which usually are found in the nucleus. Receptors, unlike enzymes, generally do not catalyze chemical changes in their ligands. (12 Dec 1998) |
| receptors, dopamine | Cell-surface proteins that bind dopamine with high affinity and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
| receptors, dopamine d1 | A class of dopamine receptors identified by their binding profiles for synthetic ligands, their molecular biology, and, perhaps, by their mode of action. (12 Dec 1998) |
| nicotinic acetylcholine receptor | Integral membrane protein of the postsynaptic membrane to which acetylcholine binds. The receptor contains an integral ion channel, as a result of binding of acetylcholine, ion channels in the subsynaptic membrane are opened. at the neuromuscular junction, the nicotinic acetylcholine receptor initiates muscle contraction. Currently the best characterised ion channel protein: made of a hetero pentamer of related subunits, although a homo pentamer is functional in insects. Structural studies show that the acetylcholine binding site and the ionic channel are part of the same macromolecular unit. The nAChR mediates rapid transduction events (1ms) whereas receptors activating G-protein coupled channels operate on slower time scales (millisecond to second range). (18 Nov 1997) |
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| nicotinic cholinergic receptor | A class of receptors responsive to acetylcholine that also are activated by nicotine; ganglionic (including the adrenal medulla) and neuromuscular receptors. Two classes exist: nicotinic-neuronal and nicotinic-muscular. (05 Mar 2000) |
| NMDA receptor | A type of glutamate receptor that participates in excitatory neurotransmission and also binds N-methyl-d-aspartate; may be particularly involved in the cell damage observed in individuals with Huntington's disease. (05 Mar 2000) |
| N methyl D aspartate receptor | <physiology> Glutamate receptor sub type (see excitatory amino acids). N methyl D aspartate receptor channels seem to be potentiated by intracellular arachidonic acid. Acronym: NMDA (26 Mar 1998) |
| quisqualate receptor | <cell biology> Glutamate operated ion channel. See: excitatory amino acid receptor channels. (05 Feb 1998) |
| insulin receptor | Areas on the outer part of a cell that allow the cell to join or bind with insulin that is in the blood. When the cell and insulin bind together, the cell can take glucose (sugar) from the blood and use it for energy. (09 Oct 1997) |
| insulin receptor protein-tyrosine kinase | <enzyme> A catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of the insulin receptor. Registry number: EC 2.7.1.- (12 Dec 1998) |
| insulin receptor substrate-1 protein | <chemical> Amino acid sequence given in first source; a 180 kD protein that contains multiple phosphorylated tyrosine residues after insulin stimulation; human and rat forms (hirs-1 and irs-1) are homologous Synonym: insulin receptor substrate-1-like protein, irs-1 protein, irs-1 gene product, hirs-1 protein, hirs-1 gene product, insulin receptor substrate 1, insulin receptor substrate-1 (05 Dec 1998) |
| oestrogen receptor | <cell biology> Cytoplasmic proteins that bind oestrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of oestrogen receptors in breast cancer patients has become clinically important and determines the likelihood of response to anti-oestrogen therapy with tamoxifen. (17 Jul 2002) |
| olfactory receptor cells | Very slender nerve cell's, with large nuclei and surmounted by six to eight long, sensitive cilia in the olfactory epithelium at the roof of the nose; they are the receptors for smell. Synonym: olfactory cells, Schultze's cells. (05 Mar 2000) |
| olfactory receptor neurons | Neurons in the olfactory epithelium with proteins (receptors, odourant) that bind, and thus detect, odourants. Olfactory receptor neurons are bipolar. They send to the surface of the epithelium apical dendrites with non-motile cilia from which project odourant receptor molecules. Their unmyelinated axons synapse in the olfactory bulb of the brain. Unlike other neurons, they can be generated from precursor cells in adults. (12 Dec 1998) |
| opiate receptor | <pharmacology> Opiate-binding sites found throughout primary afferents and the neuraxis. (16 Dec 1997) |
| opioid receptor | <pharmacology> A membrane protein, widely distributed in animal cells, but especially in the brain (enkephalin receptors) and gut. The natural ligands are the opiate peptide neurotransmitters, but the name is given because opiates are potent agonists that occupy the receptors and mimic the action of the natural transmitters. (18 Nov 1997) |
| T-cell receptor | <immunology> The antigen recognising receptor on the surface of T-cells. Heterodimeric (disulphide linked), one of the immunoglobulin superfamily of proteins, binds antigen in association with the major histocompatibility complex (MHC), leading to the activation of the cell. There are two subunits (_ and _, 42-44 kD in mouse, 50-40 kD in humans), each with variable and constant regions, that are associated noncovalently with T3 (20-30 kD). A second heterodimer on CD3 cells with _ (35 kD in mice, 55 kD in humans) and _ (45 kD in mice, 40 kD in humans) chains is a second T-cell antigen receptor that is not MHC restricted. The __ T-cell receptors (TCRs) are formed on very early T-cells in the thymus. (18 Nov 1997) |
| TCK receptor-tyrosine kinase | <enzyme> A member of the eph receptor tyrosine kinase subfamily; expressed during xenopus development; shows 79% amino acid identity to hek2; genbank l43621 Registry number: EC 2.7.1.- Synonym: tck protein (26 Jun 1999) |
Synonyms : CCK(1) Receptor, A Receptor, Cholecystokinin, CCK A Receptor, Receptor, CCK-A
Synonyms : CCK-B Receptors, CCK2 Receptor, CKK-2 Receptor, Cholecystokinin B Receptor, Cholecystokinin-2 Receptor, Gastrin Receptor, Receptor, CCK-B, B Receptor, Cholecystokinin, CCK B Receptor, CCK B Receptors, CKK 2 Receptor, Cholecystokinin 2 Receptor, Gastrin Receptors
Synonyms : Receptor, CNTF
Synonyms : Receptor, Endothelin-1, Endothelin A Receptor, Endothelin-1 Receptor, Receptor, Endothelin 1, Receptors, Endothelin A
Synonyms : Endothelin B-2 Receptors, Endothelin B 2 Receptor, Endothelin B 2 Receptors, Endothelin B Receptor, Receptor, Endothelin B-2, Receptors, Endothelin B, Receptors, Endothelin B-2
| receptor |
The receptor is the ending of a nerve where an impulse starts. This ending is usually on the skin or near the surface and is the cause of "pain" as we know it.
출처: paperairplane.mit.edu/16.423J/Space/SBE/neurovesti...
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| receptor |
A cell or group of cells that receive stimuli.
출처: www.memorydisorder.org/glossaryterms.htm
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| receptor protein |
A substance that lets a cell recognize a chemical messenger. Receptors and chemical messengers, such as hormones, work like a lock and key. The key is the hormone and the lock is the receptor. A receptor will only link up with a chemical that has a certain shape that allows it to bind to the receptor.
출처: envirocancer.cornell.edu/Glossary/GL.index.cfm
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| receptor |
Generally, a surface-exposed membrane protein on a cell which binds to a specific ligand molecule with high affinity, in order to transmit an extracellular signal and trigger intracellular biochemical events within the target cell.
출처: www.qdots.com/live/render/content.asp
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| receptor |
a docking site which interacts with a ligand; receptors may be on the cell membrane or within the cell cytoplasm or nucleus; estrogen receptors and androgen receptors are examples; all cells have multiple receptors
출처: www.prostate-cancer.org/resource/gloss_r.html
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