| heteroduplex DNA | <molecular biology> This is DNA that contains complementary strands from two different DNA molecules with similar sequences. (09 Oct 1997) |
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| highly repetitive DNA | <molecular biology> The fraction of the eukaryotic genome which consists of a short sequence of nucleotides that is repeated thousands of times all over the genome. Highly repetitive DNA is very similar to satellite DNA. (09 Oct 1997) |
| PspPI DNA methyltransferase | <enzyme> Methylates first cytosine in ggncc Registry number: EC 2.1.1.- Synonym: psppi methyltransferase, mtase (psppi), psppim gene product (26 Jun 1999) |
| selfish DNA | <molecular biology> DNA that seemingly exists only for the sake of existing and is never expressed in the phenotype. (09 Oct 1997) |
| sequence analysis, DNA | A multistage process that includes DNA cloning, physical mapping, subcloning, sequencing, and information analysis. New technological advances have led to the automation of certain steps in this process and contribute to the potential for large-scale DNA sequencing efforts. (12 Dec 1998) |
| Pyrococcus sp GB-D DNA polymerase | <enzyme> Thermophilic enzyme from the archaeon pyrococcus; used in pcr site-directed mutagenesis Registry number: EC 2.7.7.- Synonym: gb-d polymerase (26 Jun 1999) |
| hybrid DNA | <molecular biology> A double-stranded DNA molecule which was made by hybridising two single-stranded DNA molecules from two different sources. If the two single-stranded DNA molecules have enough nucleotide sequences in common, they are able to form hydrogen bonds to each other's common sequences. (09 Oct 1997) |
| hydroxymethyluracil DNA glycosylase | <enzyme> Functions to eliminate hydroxymethyluracil from oxidatively damaged DNA Registry number: EC 3.2.2.- Synonym: hmu DNA glycosylase (26 Jun 1999) |
| single stranded DNA | <molecular biology> DNA that consists of only one chain of nucleotides rather than the two base pairing strands found in DNA in the double helix form. Parvoviridae have a single stranded DNA genome. Single stranded DNA can be produced experimentally by rapidly cooling heat denatured DNA. Heating causes the strands to separate and rapid cooling prevents renaturation. (18 Nov 1997) |
| single stranded DNA dependent ATPase | <enzyme> Probably involved in DNA replication Registry number: EC 3.6.1.- Synonym: ssdna-dependent atpase (26 Jun 1999) |
| site-specific DNA-methyltransferase (adenine-specific) | <enzyme> An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyses the methylation of DNA adenine in the presence of s-adenosyl-l-methionine to form DNA containing 6-methylaminopurine and s-adenosyl-l-homocysteine. Registry number: EC 2.1.1.72 (12 Dec 1998) |
| site-specific DNA methyltransferase (cytosine-specific) | <enzyme> An enzyme responsible for producing a species-characteristic methylation pattern on cytosine residues in a specific short base sequence in the host cell's DNA. The enzyme catalyses the methylation of DNA cytosine in the presence of s-adenosyl-l-methionine to form s-adenosyl-l-homocysteine and DNA containing 5-methylcytosine. Registry number: EC 2.1.1.73 (12 Dec 1998) |
| spacer DNA | <molecular biology> The DNA sequence between genes. In bacteria, only a few nucleotides long. In eukaryotes, can be extensive and include repetitive DNA, comprising the majority of the DNA of the genome. The term is used particularly for the spacer DNA between the many tandemly repeated copies of the ribosomal RNA genes. (18 Nov 1997) |
| sticky-ended DNA | Double-stranded DNA in which one of the strands protrudes from the other strand (i.e., has a number of unpaired bases) at one end or more. (05 Mar 2000) |
| noncoding DNA | <molecular biology> DNA that does not code for part of a polypeptide chain or RNA.This includes introns and pseudo genes. In eukaryotes the majority of the DNA is noncoding. Noncoding strand refers to the so called nonsense strand, as opposed to the sense strand which is actually translated into mRNA. (18 Nov 1997) |