| tuberous sclerosis | <radiology> (Bourneville disease) autosomal dominant phakomatosis classic triad: seizures, retardation, adenoma sebaceum, calcified subependymal hamartomas, uncalcified tubers in cerebral cortex, enhancing lesion most likely to be malignant transformation to giant cell astrocytoma associated with: skin lesions, angiomyolipoma, increased risk of renal cell carcinoma (12 Dec 1998) |
|---|---|
| unicellular sclerosis | A growth of fibrous tissue between and isolating the individual cells of a part. (05 Mar 2000) |
| focal sclerosis | <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still uncertain. (18 Nov 1997) |
| focal sclerosis with hyalinosis | <nephrology> A kidney disorder that results in fibrosis and scarring in the kidney glomerulus. The cause is unknown but some cases can result from reflux nephropathy. The clinical manifestation of this kidney disorder is nephrotic syndrome. Symptoms include weight gain, swelling, hypertension and foamy urine. High blood cholesterol and triglyceride levels are also seen with this disorder. Treatment has included the use of corticosteroids and immunosuppressives. Antihypertensive agents and diuretics may also be necessary. Over one-half will develop chronic renal failure within 10 years of diagnosis. (27 Sep 1997) |
| laminar cortical sclerosis | A degeneration of nerve fibres in the corona radiata in a laminar pattern. (05 Mar 2000) |
| lateral spinal sclerosis | Considered by many to be a subgroup of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski signs are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion. Synonym: lateral spinal sclerosis. (05 Mar 2000) |
| lobar sclerosis | Circumscribed atrophy of the cerebral cortex. Synonym: lobar sclerosis, progressive circumscribed cerebral atrophy. (05 Mar 2000) |
| acute primary haemorrhagic meningoencephalitis | A disease characterised by acute onset of fever, followed by convulsions, delirium, and coma, and associated with perivascular demyelination and haemorrhagic foci in the central nervous system. Synonym: acute primary haemorrhagic meningoencephalitis, Strumpell's disease. (05 Mar 2000) |
| acyclic monoterpene primary alcohol - NADP oxidoreductase | <enzyme> From catmint nepeta racemosa; involved in the biosynthesis of iridoid monoterpenes; oxidises geraniol, nerol, and their 10-hydroxy derivatives in the presence of nadp(+). Registry number: EC 1.1.1.- Synonym: monoterpene primary alcohol - nadp oxidoreductase, ampano (26 Jun 1999) |
| anterior primary division | <anatomy, nerve> The larger, anterolaterally-directed major terminal branch (with the dorsal primary ramus) of all 31 pairs of mixed spinal nerves, formed at the intervertebral foramen. Most ventral primary rami, especially those involved in the innervation of the limbs, participate in the formation of the major nerve plexuses (cervical, brachial, and lumbosacral) and lose their identities. Most in the thoracic region, however, remain separate from adjacent rami to become the intercostal and subcostal nerves. Ventral primary rami provide innervation to the anterolateral body wall and trunk. Nomina Anatomica lists ventral primary rami as "rami ventrales" for each group of spinal nerves: 1) cervical (nervorum cervicalium ), 2) thoracic (nervorum thoracicorum ), 3) lumbar (nervorum lumbalium ), 4) sacral (nervorum sacralium )m, and 5) coccygeal (nervi coccygei ). Synonym: ramus ventralis nervi spinalis, anterior primary division. (05 Mar 2000) |
| aphasia, primary progressive | A type of aphasia appearing gradually and gradually worsening without any major change in other cognitive functions. It is regarded by some authors as a syndrome which may be due to various degenerative diseases of the cerebral cortex (notably alzheimer disease, owing to its frequency), while others see in it an autonomous disease related to a neuropathological process that is distinct from the main degenerative dementias. The principal clinical peculiarity of primary progressive aphasia is that it spares the patient's autonomy for a long time, but ultimately turns into global dementia. (12 Dec 1998) |
| ventral primary rami of cervical spinal nerves | See: ventral primary ramus of spinal nerve. Synonym: rami ventrales nervorum cervicalium. (05 Mar 2000) |
| ventral primary rami of lumbar spinal nerves | See: ventral primary ramus of spinal nerve. Synonym: rami ventrales nervorum lumbalium. (05 Mar 2000) |
| ventral primary rami of sacral spinal nerves | See: ventral primary ramus of spinal nerve. Synonym: rami ventrales nervorum sacralium. (05 Mar 2000) |
| ventral primary ramus of spinal nerve | <anatomy, nerve> The larger, anterolaterally-directed major terminal branch (with the dorsal primary ramus) of all 31 pairs of mixed spinal nerves, formed at the intervertebral foramen. Most ventral primary rami, especially those involved in the innervation of the limbs, participate in the formation of the major nerve plexuses (cervical, brachial, and lumbosacral) and lose their identities. Most in the thoracic region, however, remain separate from adjacent rami to become the intercostal and subcostal nerves. Ventral primary rami provide innervation to the anterolateral body wall and trunk. Nomina Anatomica lists ventral primary rami as "rami ventrales" for each group of spinal nerves: 1) cervical (nervorum cervicalium ), 2) thoracic (nervorum thoracicorum ), 3) lumbar (nervorum lumbalium ), 4) sacral (nervorum sacralium )m, and 5) coccygeal (nervi coccygei ). Synonym: ramus ventralis nervi spinalis, anterior primary division. (05 Mar 2000) |