| mucolipidosis III | <biochemistry> Mucolipidosis with mild Hurler-like symptoms, restricted joint mobility, short stature, mild mental retardation, and dysplastic skeletal changes, especially of the hip. Aortic and mitral valve disease are often present. It is associated with a deficiency of UDP-N-acetyl glucosamine and lysosomal enzyme N-acetylglucosaminyl-1-phosphotransferase. Inheritance: autosomal recessive. Synonym: pseudo-Hurler polydystrophy, pseudopolydystrophy. (05 Mar 2000) |
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| mucopolysaccharidosis III | Mucopolysaccharidosis characterised by heparitin sulfate in the urine, progressive mental retardation, mild dwarfism, and other skeletal disorders. There are four clinically indistinguishable but biochemically distinct forms, each due to a deficiency of a different enzyme. (12 Dec 1998) |
| congenital antithrombin III deficiency | Antithrombin III is a protein which stimulates the removal of blood clots in the bloodstream. Small blood clots form normally within the bloodstream, but are normally dissolved via the bodys antithrombin III. The deficiency of antithrombin III will result in an increased risk for blood clot formation causing organ damage. This is an inherited as a autosomal dominant trait. Inheritance: autosomal dominant. (27 Sep 1997) |
| connective tissue activating peptide III | Cytokine, produced from platelet basic protein, that acts as a growth factor. (18 Nov 1997) |
| mycinamicin III O-methyltransferase | <enzyme> Catalyses the incorporation of the methyl group of s-adenosyl-l-methionine at the 3'' position of mycinamicin III; from micromonospora griseorubida; genbank d16097 Registry number: EC 2.1.1.- Synonym: mycf gene product, miii o-mtase (26 Jun 1999) |
| cranial mononeuropathy III | (compression type) A disorder involving vision changes and eyelid drooping associated with a decreased functioning of cranial nerve III. Damage is usually caused by compression of the nerves from localised lesions or a swelling in the area of the nerve. Examples include cerebral aneurysms and tumours Symptoms include a drooping eyelid and double vision. (diabetic type) A disorder involving vision changes and eyelid drooping associated with a decreased functioning of cranial nerve III as a complication of diabetes. Symptoms include a drooping eyelid and double vision. Good control of blood sugars can reduce the incidence of this complication. (27 Sep 1997) |
| cranial nerve III | <anatomy, nerve> The occulomotor nerve is responsible for motor enervation of upper eyelid muscle, extraocular muscle and pupillary muscle. Lesions of the oculomotor nerve results in ptosis (dropping eyelid), deviation of the eyeball outward, double vision and a dilated pupil. Synonym: cranial nerve III. (27 Sep 1997) |
| processus styloideus ossis metacarpalis III | A pointed projection from the dorsolateral angle of the base of the third metacarpal bone; it sometimes exists as a separate ossicle. Synonym: processus styloideus ossis metacarpalis III. (05 Mar 2000) |
| protoporphyrinogen type III | The immediate precursor of protoporphyrin III in haem biosynthesis; elevated in cases of variegate porphyria. (05 Mar 2000) |
| protoporphyrinogen type III oxidase | A mitochondrial enzyme that uses O2 to convert protoporphyrinogen type III to protoporphyrin type III in haem biosynthesis; a deficiency of this enzyme is associated with variegate porphyria. (05 Mar 2000) |
| protoporphyrin type III | 2,7,12,18-Tetramethyl-3,8-divinylporphin-13,17dipropionic acid;the principal protoporphyrin found in nature (one of 15 possible isomers), characterised by the presence of 4 methyl groups, 2 vinyl groups, and 2 propionic acid side chains; a porphyrin derivative that, with iron, forms the haem of haemoglobin and the prosthetic groups of myoglobin, catalase, cytochromes, etc. (05 Mar 2000) |
| Hind III | <enzyme, molecular biology> Commonly used type II restriction endonuclease isolated from Haemophilus influenzae, it cleaves the sequence AAGCTT between the two As thus generating sticky ends. (18 Nov 1997) |
| HTLV-III | <abbreviation> Human T-cell lymphotropic virus type III. See: human immunodeficiency virus. (05 Mar 2000) |
| hyperlipoproteinaemia type III | A rather uncommon form of familial hyperlipaemia characterised by the presence of lipoproteins of abnormal composition. The main abnormal lipoproteins are called beta-vldl and have a different apoprotein content and a higher proportion of cholesterol relative to triglyceride than normal vldl. (12 Dec 1998) |
| NADH-Fe(III)EDTA oxidoreductase | <enzyme> From cryptococcus albidus; catalyses the formation of nad+ and fe(ii)edta from NADH and fe(iii)edta; forms ethylene from 2-oxo-4-methylthiobutyric acid Registry number: EC 1.6.99.- (26 Jun 1999) |