| IRS | immunoreactive secretion; infrared spectrophotometry; insulin receptor species; insulin receptor sub... |
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| CGRP | Calcitonin Gene Related Peptide(Protein) |
| CLIP | Corticotropin-Like Intermediate Peptide |
| DSIP | Delta Sleep Inducing Peptide |
| GIP | 1) Giant cell Interstitial Pneumonia 2) Gastric Inhibitory (Poly)Peptide |
| cyclic peptide | A peptide that forms a ring structure; e.g., tyrocidin A, an antibiotic, is a cyclic decapeptide; valinomycin is a cyclic depsipeptide. (05 Mar 2000) |
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| prenylated peptide-specific endoprotease | <enzyme> Cleaves c-terminal tripeptide from prenylated protein having c-terminal sequence caax; race is rac and a-factor converting enzyme with same activity Registry number: EC 3.4.14.- Synonym: prenylated protein endoprotease, race enzyme, isoprenylated protein endopeptidase, isoprenylated protein endoprotease (26 Jun 1999) |
| heterodetic peptide | A peptide that contains peptide bonds as well as covalent linkages between certain amino acid residues that are not peptide bonds; e.g., valinomycin, oxytocin. Origin: hetero-+ G. Detos, bound, fr. Deo, to bind, + -ic (05 Mar 2000) |
| heteromeric peptide | A peptide which, on hydrolysis, yields substances other than amino acids in addition to amino acids; e.g., pteroylglutamic acid. (05 Mar 2000) |
| homodetic peptide | A peptide in which all of the covalent linkages between the constituent amino acids are peptide bonds; e.g., bradykinin. Origin: homo-+ G. Detos, bound, fr. Deo, to bind, + -ic (05 Mar 2000) |
| homomeric peptide | A peptide which, on hydrolysis, yields only amino acids; e.g., glutathione, A peptide which consists of only one particular amino acid; e.g., alanylalanylalanine. (05 Mar 2000) |
| sigma peptide | A peptide with one end bonded to a point within the chain, usually by means of the disulfide group of a cystine residue, so that only one end of the peptide is free; so called since the peptide chain has then the rough shape of the Greek letter sigma; e.g., oxytocin. (05 Mar 2000) |
| signal peptide | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide p25-subunit IV cytochrome oxidase | <chemical> Similar in action to melittin Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25 (26 Jun 1999) |
| non-ribosomal peptide synthase | <enzyme> Nrp - non-ribosomal peptide/polyketide; locus nrp is mutated in a swarming-defective proteus mirabilis strain; 249 amino acid residues, mw 29.7 kD; amimo acid sequence given in first source Registry number: EC 6.3.2.- Synonym: nrpg protein, nrpg gene product (26 Jun 1999) |
| delta sleep-inducing peptide | <chemical> A nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal. Chemical name: Delta sleep-inducing peptide (12 Dec 1998) |
| diabetes related peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
| insulin c-peptide | <investigation> A blood test which measures the amount of C-peptide in the blood. C-peptide is a byproduct of normal insulin production by the beta cells in the pancreas. Normal values are 0.5 to 3.0 ng/ml. Normal levels indicate that the body is still producing its own insulin. Low levels indicate that the pancreas is producing little or no insulin. Elevations can be seen in cases of insulinomas and islet of Langerhans tumours. (27 Sep 1997) |
| insulin-stimulating peptide | <chemical> 71-amino acid containing peptide; corresponds to residues 115-143 and 144-184 of bovine serum albumin with the exception of a tyrosine insertion between residues 155 and 156; consists of two chains with mw 5000 and 3400 for each chain Synonym: h-isp, insulin-stimulating protein (05 Dec 1998) |
| islet amyloid peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |