| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
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| fibrous cortical defect | A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. See: nonossifying fibroma. Synonym: nonosteogenic fibroma. (05 Mar 2000) |
| uterine filling defect | <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op) (12 Dec 1998) |
| filling defect | Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (05 Mar 2000) |
| filling defect in renal collecting system | <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases (12 Dec 1998) |
| lambdoid suture defect | <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis (12 Dec 1998) |
| luteal phase defect | Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss. (09 Oct 1997) |
| activated partial thromboplastin time | The time needed for plasma to form a fibrin clot following the addition of calcium and a phospholipid reagent; used to evaluate the intrinsic clotting system. (05 Mar 2000) |
| reaction of partial identity | See: gel diffusion precipitin tests in two dimensions. (05 Mar 2000) |
| partial | 1. Of, pertaining to, or affecting, a part only; not general or universal; not total or entire; as, a partial eclipse of the moon. "Partial dissolutions of the earth." 2. Inclined to favor one party in a cause, or one side of a question, more then the other; baised; not indifferent; as, a judge should not be partial. "Ye have been partial in the law." (Mal. Ii. 9) 3. Having a predelection for; inclined to favor unreasonably; foolishly fond. "A partial parent." "Not partial to an ostentatious display." (Sir W. Scott) 4. <botany> Pertaining to a subordinate portion; as, a compound umbel is made up of a several partial umbels; a leaflet is often supported by a partial petiole. Partial differentials, Partial differential coefficients, Partial differentiation, etc. (of a function of two or more variables), the differentials, differential coefficients, differentiation etc, of the function, upon the hypothesis that some of the variables are for the time constant. <mathematics> Partial fractions, the simple tones which in combination form an ordinary tone; the overtones, or harmonics, which, blending with a fundamental tone, cause its special quality of sound, or timbre, or tone colour. See, also, Tone. Origin: F, fr. LL. Partials, fr. L. Pars, gen. Partis, a part; cf. (for sense 1) F. Partiel. See Part. Source: Websters Dictionary (01 Mar 1998) |
| partial adrenocortical insufficiency | Normal basal adrenocortical function with failure of adrenocortical reserve to respond to ACTH stimulation. (05 Mar 2000) |
| partial agglutinin | Immune agglutinin present in an antiserum in lesser concentration than the major agglutinin. Synonym: partial agglutinin. (05 Mar 2000) |
| partial anencephaly | Congenital failure of the cerebrum to develop normally; usually the cerebellum and basal ganglia are represented at least in rudimentary form. Synonym: partial anencephaly. Origin: hemi-+ G. Kephale, head (05 Mar 2000) |
| partial aneuploidy | A type of mosaicism in which some cells have a normal number of chromosomes and some have an abnormal number. (05 Mar 2000) |
| partial anodontia | A condition of having fewer than the normal complement of teeth, either congenital or acquired. Synonym: oligodontia, partial anodontia. Origin: hypo-+ G. Odous, tooth (05 Mar 2000) |