| oligonephronic | Characterised by a reduced number of nephrons. (05 Mar 2000) |
|---|---|
| oligonucleotidase | <enzyme> From flammulina veluptis; catalyses exonucleolytic cleavage of oligonucleotides to yield 5'-phosphomononucleotides; also hydrolyzes nad+ to nmn and AMP; formerly EC 3.1.4.19 Registry number: EC 3.1.13.3 (26 Jun 1999) |
| oligonucleotide | <biochemistry> Linear sequence of up to 20 nucleotides joined by phosphodiester bonds. Above this length the term polynucleotide begins to be used. (18 Nov 1997) |
| oligonucleotide probes | Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridises with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32p and 125i and the chemical label biotin. (12 Dec 1998) |
| oligonucleotides | Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesised to match a region where a mutation is known to occur, and then used as a probe (oligonucleotide probes). (12 Dec 1998) |
| oligonucleotides, antisense | Short fragments (usually between 2 and 12 nucleotides) of DNA or RNA that are used to hinder or block the translation or processing of mRNA. (12 Dec 1998) |
| oligopepsia | Impaired digestion, especially that due to a deficiency of pepsin. Synonym: oligopepsia. Origin: hypo-+ G. Pepsis, digestion (05 Mar 2000) |
| oligopeptidase | <enzyme> From bacillus spaericus; acts on dipeptides and some tri- or tetrapeptides with ala-ala Registry number: EC 3.4.- (26 Jun 1999) |
| oligopeptide | <biochemistry> A peptide of a small number of component amino acids as opposed to a polypeptide. Exact size range is a matter of opinion but peptides from 3 to about 40 member amino acids might be so described. (18 Nov 1997) |
| oligopeptide 20 | A compound made up of the condensation of a small number (typically less than 20) of amino acids. Compare: polypeptide. (05 Mar 2000) |
| oligopeptide permease | <chemical> Bacterial; does not act on free amino acids; takes up dipeptides and oligopeptides of up to 5 amino acids; spo0k, an abc transporter, isolated from bacillus subtilis; see also oppb protein and oppc protein Chemical name: permease, oligopeptide Synonym: dipeptide permease, tripeptide permease, spo0k gene product, oppa protein, oligopeptide permease, oppd protein, oppf protein (26 Jun 1999) |
| oligopeptides | Peptides composed of between two and twelve amino acids. (12 Dec 1998) |
| oligopetalous | <botany> Having few petals. Origin: Oligo- + petal. Source: Websters Dictionary (01 Mar 1998) |
| oligophosphoglyceroyl-ATP 3'-phosphodiesterase | <enzyme> Located in mitochondrial fraction of rat liver; selectively hydrolyzes the oligo cpd to monomeric units of 3-phosphoglyceroyl-gamma-triphospho-5'-adenosine Registry number: EC 3.1.4.- Synonym: opg-ATP-phosphodiesterase (26 Jun 1999) |
| oligophrenia | Synonym: mental retardation. (05 Mar 2000) |