| DR | degeneration reaction; delivery room; deoxyribose; diabetic retinopathy; diagnostic radiology; digit... |
|---|---|
| ERA | electrical response activity; electroencephalic response audiometry; Electroshock Research Associati... |
| ERP | early receptor potential; effective refractory period; elodoisin-related peptide; endoscopic retrogr... |
| GCGR | glucagon receptor; glucocorticoid receptor |
| INSRR | insulin receptor-related receptor |
| olfactory roots | Three distinct fibre bands (stria medialis, stria intermedia, stria lateralis) that caudally extend the olfactory tract beyond its attachment to the olfactory trigone. The medial stria curves dorsally into the tenia tecta; the intermediate, often barely visible, extends straight back and terminates in the olfactory tubercle; the lateral olfactory stria, the largest of the three, passes along the lateral side of the olfactory tubercle, curving laterally as far as the limen insulae, then sharply medially to reach the uncus of the parahippocampal gyrus where it terminates in the plexiform layer of the olfactory cortex. See: medial longitudinal stria. Synonym: striae olfactoriae, olfactory roots. (05 Mar 2000) |
|---|---|
| olfactory striae | Three distinct fibre bands (stria medialis, stria intermedia, stria lateralis) that caudally extend the olfactory tract beyond its attachment to the olfactory trigone. The medial stria curves dorsally into the tenia tecta; the intermediate, often barely visible, extends straight back and terminates in the olfactory tubercle; the lateral olfactory stria, the largest of the three, passes along the lateral side of the olfactory tubercle, curving laterally as far as the limen insulae, then sharply medially to reach the uncus of the parahippocampal gyrus where it terminates in the plexiform layer of the olfactory cortex. See: medial longitudinal stria. Synonym: striae olfactoriae, olfactory roots. (05 Mar 2000) |
| olfactory sulcus | The sagittal sulcus on the inferior or orbital surface of each frontal lobe of the cerebrum, demarcating the straight gyrus from the orbital gyri, and covered on the orbital surface by the olfactory bulb and tract. Synonym: sulcus olfactorius, olfactory groove. (05 Mar 2000) |
| olfactory sulcus of nasal cavity | The narrow groove in the nasal cavity above the agger nasi that leads from the atrium to the olfactory area. Synonym: sulcus olfactorius cavum nasi. (05 Mar 2000) |
| olfactory tract | A nervelike, white band composed primarily of nerve fibres originating from the mitral cells and tufted cells of the olfactory bulb but also containing the scattered cells of the anterior olfactory nucleus. The tract is closely applied to the ventral surface of the frontal lobe, and attaches itself to the base of the cerebral hemisphere at the olfactory trigone, beyond which it extends in the form of the olfactory striae which distribute their fibres to the olfactory tubercle and, in largest number, to the olfactory cortex on and around the uncus of the parahippocampal gyrus. See: olfactory nerves. Synonym: tractus olfactorius, olfactory peduncle. (05 Mar 2000) |
| olfactory trigone | A grayish triangular area corresponding to the attachment of the olfactory peduncle ("olfactory nerve" or olfactory tract) to the base of the brain, at the anterior border of the anterior perforated substance. Synonym: trigonum olfactorium. (05 Mar 2000) |
| olfactory tubercle | A small, oval area at the base of the cerebral hemisphere, between the diverging medial and lateral olfactory striae, in the anteromedial part of the anterior perforated substance; it is formed by a small area of allocortex characterised by the presence of the islands of Calleja. Corresponding to a much more prominent structure in nonprimate mammals (especially rodents and insectivores), the olfactory tubercle receives fibres from the olfactory bulb by way of the intermediate olfactory stria; it has efferent connections with the hypothalamus and the mediodorsal nucleus of the thalamus. Synonym: tuberculum olfactorium. (05 Mar 2000) |
| acetylcholine receptor antibodies | <neurology, investigation> A test used to measure the amount of antibodies to acetylcholine receptors on nerve endings. This is a diagnostic test for myasthenia gravis. A normal value is no antibodies in the bloodstream. Acetylcholine receptor (AChR) binding autoantibodies (i.e. Antibodies reactive with several epitopes other than the binding site for acetylcholine or alpha-bungarotoxin) are present in approximately 88% of patients with generalised myasthenia gravis, 70% of ocular myasthenia and in approximately 80% of myasthenia gravis in remission. Although serum concentrations of AChR binding autoantibodies do not in general correlate well with severity of weakness, there is typical decrease in concentration as weakness improves with immunosuppressive therapy. AChR blocking autoantibodies (i.e., antibodies reactive with the AChR binding site) are present in about 50% of patients with myasthenia gravis, 30% with ocular myasthenia gravis and 20% of myasthenia gravis in remission, AChR blocking autoantibodies are the only AChR autoantibodies present in about 1% of myasthenia gravis. AChR modulating autoantibodies (i.e., autoantibodies which cross-link AChRs and cause their removal from muscle membrane surfaces) are present in more than 90% of myasthenia gravis and occasionally are the only AchR autoantibodies detectable in mild, recent onset or ocular-restricted myasthenia gravis. Results for AChR modulating autoantibodies can be transiently false-positive due to curare-like drugs used during general anesthesia. AChR autoantibodies of one or more types are found in at least 80% of ocular myasthenia gravis. Although generally absent in neurological conditions other than myasthenia gravis(and consequently unlikely to cause confusion in neurodiagnosis), false-positive results for AChR autoantibodies occasionally occur in primary biliary cirrhosis, tardive dyskinesia, autoimmune thyroiditis, the elderly, amyotrophic lateral sclerosis patients treated with cobra venom and patients with thymoma in the absence of myasthenia gravis. Approximately 1% of patients with rheumatoid arthritis treated with D-penicillamine develop AChR autoantibodies and myasthenia gravis, both of which disappear when the drug is discontinued. Babies born to ~10% of myasthenia gravis mothers have a transient neonatal form of myasthenia gravis that responds well to anticholinesterase therapy and usually remits within 1 month as maternal IgG disappears. (29 Dec 1997) |
| amino acid receptor | <biochemistry> Ligand gated ion channels with specific receptors for amino acid transmitters. An extended protein superfamily that also includes subunits of the nicotinic acetylcholine receptor. (18 Nov 1997) |
| AMPA receptor | <cell biology> Glutamate operated ion channel. See: excitatory amino acid receptor channels. (05 Feb 1998) |
| ANP receptor | <molecular biology> Family of 3 receptors for atrial natriuretic peptide. ANP A and ANP B have intracellular guanylate cyclase and protein kinase like domains. ANP C, shares the extracellular ligand binding and transmembrane domains, but lacks the functional intracellular domains and is not thought to be involved in signal transduction. (18 Nov 1997) |
| asialoglycoprotein receptor | A surface receptor found in hepatocytes that binds galactose-terminal glycoproteins; thus, this receptor removes those proteins from circulation and they are in turn acted upon by hepatocyte lysosomes. (05 Mar 2000) |
| auditory receptor cells | Columnar cell's in the epithelium of the organ of Corti, having hairs (stereocilia) on their apical ends. See: Corti's cells. (05 Mar 2000) |
| beta-adrenergic receptor blocking agent | A class of drugs that compete with beta-adrenergic agonists for available receptor sites; some compete for both b1 and b2 receptors (e.g., propranolol) while others are primarily either b1 (e.g., metoprolol) or b2 blockers; used in the treatment of a variety of cardiovascular diseases where beta-adrenergic blockade is desirable. Synonym: beta-adrenergic receptor blocking agent, beta-adrenoreceptor antagonist, beta-blocker. (05 Mar 2000) |
| beta-adrenergic receptor kinase | <enzyme> Cyclic-AMP protein kinase which specifically phosphorylates the agonist-occupied form of beta-adrenergic receptor Registry number: EC 2.7.1.- Synonym: beta-ar kinase, beta-adrenergic receptor kinase 1, g-protein-coupled receptor kinase 2, grk2 (kinase), beta-adrenergic receptor kinase 2, beta-ar kinase 2 (26 Jun 1999) |