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nucleorrhexis Fragmentation of a cell nucleus.
Origin: nucleo-+ G. Rhexis, rupture
(05 Mar 2000)
nucleosidase <enzyme> Catalyses hydrolysis of n-ribosyl-purine into a purine and d-ribose
Registry number: EC 3.2.2.1
Synonym: purine nucleoside hydrolase, guanosine hydrolase
(26 Jun 1999)
nucleosidases <enzyme> Registry number: EC 3.2.2.
(12 Dec 1998)
nucleoside <biochemistry> Purine or pyrimidine base linked glycosidically to ribose or deoxyribose, but lacking the phosphate residues that would make it a nucleotide.
Ribonucleosides are adenosine, guanosine, cytidine and uridine. Deoxyribosides are deoxyadenosine, deoxyguanosine, deoxycytidine and deoxythymidine (the latter is almost universally referred to as thymidine).
(18 Nov 1997)
nucleoside analogue A synthetic molecule that resembles a naturally occuring nucleoside, but that lacks a bond site needed to link it to an adjacent nucleotide.
(09 Oct 1997)
nucleoside bisphosphate A nucleoside that carries two independent (i.e., not linked to each other) phosphoric residues.
Compare: nucleoside diphosphate.
(05 Mar 2000)
nucleoside deaminases <enzyme> Catalyze the hydrolysis of nucleosides with the elimination of ammonia.
Registry number: EC 3.5.4
(12 Dec 1998)
nucleoside diphosphate The pyrophosphoric ester of a nucleoside, i.e., a nucleoside in which the H of one of the ribose hydroxyls (usually the 5') is replaced by a pyrophosphoric (diphosphoric) radical; e.g., adenosine 5'-diphosphate.
Compare: nucleoside bisphosphate.
(05 Mar 2000)
nucleoside phosphorylase <enzyme> From klebsiella sp.; acts on both purine and pyrimidine nucleosides and catalyses the production of araa from uridine arabinoside (arau) and adenine
Registry number: EC 2.4.2.-
(26 Jun 1999)
nucleoside phosphorylases Enzymes that catalyze the phosphorolysis of a nucleoside, forming the free purine or pyrimidine plus ribose (or deoxyribose 1-phosphate); e.g., purine-nucleoside phosphorylases.
(05 Mar 2000)
nucleoside q <chemical> (1s-(1 alpha,4 beta,5 beta))-2-amino-5-(((4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-7-beta-d-ribofuranosyl-4h-pyrrolo(2,3-d)pyrimidin-4-one. A modified nucleoside which is present in the first position of the anticodon of trna-tyrosine, trna-histidine, trna-asparagine and trna-aspartic acid of many organisms. It is believed to play a role in the regulatory function of trna. Nucleoside q can be further modified to nucleoside q*, which has a mannose or galactose moiety linked to position 4 of its cyclopentenediol moiety.
Chemical name: 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-5-(((4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-7-beta-D-ribofuranosyl-, (1S-(1alpha,4beta,5beta))-
(12 Dec 1998)
nucleoside triphosphate A nucleoside in which the H of one of the ribose hydroxyls (usually the 5') is replaced by a triphosphoric group, -PO(OH)-O-PO(OH)-O-PO(OH)2; e.g., adenosine triphosphate.
(05 Mar 2000)
nucleoside triphosphate-adenylate kinase <enzyme> Other nucleoside triphosphates may replace GTP as substrate
Registry number: EC 2.7.4.10
Synonym: GTP-AMP phosphotransferase, AMP-GTP phosphotransferase
(26 Jun 1999)
nucleoside-diphosphate kinase <enzyme> A phosphotransferase enzyme that is found in mitochondria and in the soluble cytoplasm of cells.
It catalyses reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside diphosphate, e.g., UDP, to form ADP and UTP. Many nucleoside diphosphates can act as acceptor, while many ribonucleoside triphosphates and deoxyribonucleoside triphosphates can act as a donor.
Chemical name: ATP:nucleoside-diphosphate phosphotransferase
Registry number: EC 2.7.4.6
(12 Dec 1998)
nucleoside-diphosphate sugars Nucleoside diphosphates linked through the 5'-diphosphoric group with simple or complex carbohydrates; e.g., GDP-mannose, UDP-glucose (UDPG), dTDP-glucosamine.
(05 Mar 2000)
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