| nuclear sap | The presumably fluid substance or gel of the nucleus in which stainable elements were believed to be suspended; much that was formerly considered to be karyolymph is now known to be euchromatin. Synonym: nuclear hyaloplasm, nuclear sap, nucleochylema, nucleochyme. Origin: karyo-+ L. Lympha, clear water (05 Mar 2000) |
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| nuclear scaffold serine protease | <enzyme> Calcium-regulated serine protease which cleaves a subset of lamins a/c (intermediate filament proteins) to produce an ATP-binding protein; partial amino-terminal amino acid sequence given in first source Registry number: EC 3.4.21.- Synonym: ns protease (26 Jun 1999) |
| nuclear scan: adrenals | A nuclear scan that images the adrenal glands after a radioactive tracer is injected into the bloodstream. This test is useful in detecting a pheochromocytoma, particularly if it not within the adrenal gland. (27 Sep 1997) |
| nuclear sclerosis | Increased refractivity of the central portion of the lens of the eye. See: nuclear cataract. (05 Mar 2000) |
| nuclear spindle | See: spindle and mitosis. (18 Nov 1997) |
| nuclear stain | <technique> A stain for cell nuclei, usually based on the binding of a basic dye to DNA or nucleohistone. (05 Mar 2000) |
| nuclear transplantation | <procedure> Experimental approach in study of nucleo cytoplasmic interactions, in which a nucleus is transferred from one cell to the cytoplasm (which may be anucleate) of a second. (18 Nov 1997) |
| nuclear transport | <cell biology> Passage of molecules in and out of the nucleus, presumably via nuclear pores. Passage of proteins into the nucleus may depend on possession of a nuclear location sequence containing five consecutive positively charged residues PKKKRKV). (18 Nov 1997) |
| nuclear warfare | Warfare involving the use of nuclear weapons. (12 Dec 1998) |
| nuclear-cytoplasmic ratio | Ratio of volume of nucleus to volume of cytoplasm, fairly constant for a particular cell type and usually increased in malignant neoplasms. (05 Mar 2000) |
| nuclease | <enzyme> An enzyme capable of cleaving the phosphodiester bonds between nucleotide subunits of nucleic acids. (18 Nov 1997) |
| nucleate | A salt of a nucleic acid. (05 Mar 2000) |
| nucleate endonuclease | A nuclease (a nucleate oligonucleotidohydrolase) that forms oligonucleotides ending in 5'-phosphates from RNA and DNA; hydrolyzes both double-stranded and single-stranded polynucleic acids. Synonym: nucleate endonuclease. (05 Mar 2000) |
| nucleated | Provided with a nucleus, a characteristic of all true cells. (05 Mar 2000) |
| nucleation | <molecular biology> A general term used in polymerisation or assembly reactions where the first steps are energetically less favoured than the continuation of growth. Polymerisation is much faster if a pre formed seed is used to nucleate growth. (e.g. Microtubule growth is nucleated from the microtubule organising centre, although the nature of this nucleation is not known). (18 Nov 1997) |