| extraction coefficient | The percentage of a substance removed from the blood or plasma in a single passage through a tissue; e.g., the extraction coefficient for p-aminohippuric acid (PAH) in the kidney is the difference between arterial and renal venous plasma PAH concentrations, divided by the arterial plasma PAH concentration. (05 Mar 2000) |
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| ultrafiltration coefficient | The filtration coefficient of a semipermeable membrane. (05 Mar 2000) |
| filtration coefficient | A measure of a membrane's permeability to water; specifically, the volume of fluid filtered in unit time through a unit area of membrane per unit pressure difference, taking into account both hydraulic and osmotic pressures. (05 Mar 2000) |
| lethal coefficient | <microbiology> That concentration of disinfectant that kills bacteria at 20-25캜 in the shortest period of time. (05 Mar 2000) |
| linear absorption coefficient | That fraction of ionizing radiation absorbed in a unit thickness of a substance or tissue. See: absorption coefficient. (05 Mar 2000) |
| Long's coefficient | A formula for estimating from the specific gravity of a specimen of urine the approximate amount of solids in grams per liter; the last two figures of the value for specific gravity are multiplied by 2.6. Synonym: Long's coefficient. (05 Mar 2000) |
| androgen binding protein | A protein secreted by testicular Sertoli cells along with inhibin and mullerian inhibiting substance. Androgen binding protein probably maintains a high concentration of androgen in the seminiferous tubules. (05 Mar 2000) |
| androgen-binding proteins | Carrier proteins produced in the sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. Participate in the transport of androgens; include also synthetic androgens binding proteins. (12 Dec 1998) |
| antigen-binding site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
| binding | <biochemistry, chemistry, molecular biology> The adherence of molecules to one another, for example, enzymes to substrates, antibodies to antigens, DNA strands to their complementary strands. Binding occurs because the shape and chemical natures of parts of the molecules surfaces are complementary. A common metaphor is the "lock-and-key," used to describe how enzymes fit around their substrate. (14 Nov 1997) |
| binding constant | <chemistry> Reciprocal of dissociation constant. A measure of the extent of a reversible association between two molecular species at equilibrium. (18 Nov 1997) |
| binding energy | <chemistry, radiobiology> The binding energy of a nucleus is the minimum energy required to dissociate it into its component neutrons and protons. Neutron or proton binding energies are those required to remove a neutron or proton, respectively, from a nucleus. Electron binding energy is that required to remove an electron from an atom or a molecule. (16 Dec 1997) |
| binding sites | The reactive parts of a macromolecule that directly participate in its specific combination with another molecule. (12 Dec 1998) |
| binding sites, antibody | Local surface sites on antibodies which react with antigen determinant sites on antigens. They are formed from parts of the variable regions of the fab fragment of the immunoglobulin. (12 Dec 1998) |
| calcium-binding protein | <biochemistry> There are two main groups of calcium binding proteins, those that are similar to calmodulin and are called EF hand proteins and those that bind calcium and phospholipid (e.g. Lipocortin) and that have been grouped under the generic name of annexins. Many other proteins will bind calcium, although the binding site usually has considerable homology with the calcium-binding domains of calmodulin. They can act as transport proteins, regulator proteins or activator proteins. There is also a vitamin D-dependent variant which is a protein that plays a fundamental role in the vitamin d mediated transport of calcium in reptiles, amphibians, birds and mammals. It is found in the intestine, kidneys, egg shell gland, brain, and possibly other organs. Its molecular weight is species dependent. (12 May 2002) |