| nodular sclerosis | <cardiology, pathology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |
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| nodular subepidermal fibrosis | A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed capillaries with scattered haemosiderin-pigmented and lipid macrophages. They are common, usually about 1 cm in diameter and occur in the dermis. Simple excision is always curative. (12 Dec 1998) |
| nodular syphilid | Origin: NL. So called from its gummy contents See Gum. <medicine> A kind of soft tumour, usually of syphilitic origin. Source: Websters Dictionary (01 Mar 1998) |
| nodular tuberculid | A type of panniculitis characterised histologically by the presence of granulomas, vasculitis, and necrosis. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is seen most commonly in adolescent and menopausal women, is initiated or exacerbated by cold weather, and typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves. The nodules may progress to form indurations, ulcerations, and scars. (12 Dec 1998) |
| nodular vasculitis | Chronic or recurrent nodular lesions of subcutaneous tissue, especially of the legs of older women, with lobular panniculitis, granulomatous inflammation with multinucleated giant cells, focal necrosis, and obliterative inflammation of the small blood vessels, resembling erythema induratum but without evidence of associated tuberculosis. (05 Mar 2000) |
| toxic nodular goitre | <endocrinology> An enlarged thyroid gland which contains nodules which release excess thyroid hormone. This condition usually arises from long-standing simple goitre in the elderly. Symptoms of hyperthyroidism result. (12 Jan 1998) |
| focal nodular hyperplasia | <radiology> Focal nodules of normal hepatocytes, Kuppfer cells and bile ducts, F more than M, rare, benign, multiple in 20%, haemorrhage (most common complication) in only 2-3% (unlike hepatic adenoma), stellate fibrous septae (stellate scar), NM: normal or increased uptake on HIDA and sulfur colloid (12 Dec 1998) |
| localised nodular tenosynovitis | A nodule, possibly inflammatory in nature, arising commonly from the flexor sheath of the fingers and thumb; composed of fibrous tissue, lipid-and haemosiderin-containing macrophages, and multinucleated giant cells. Synonym: localised nodular tenosynovitis. (05 Mar 2000) |
| acute yellow atrophy of the liver | A lesion in which there is extensive and rapid death of parenchymal cells of the liver, sometimes with fatty degeneration of the size of the organ; the necrosis may result from fulminant viral infection or chemical poisoning; associated with jaundice. Synonym: acute parenchymatous hepatitis, Rokitansky's disease. (05 Mar 2000) |
| adenoma, liver cell | A benign epithelial tumour of the liver. (12 Dec 1998) |
| alcoholic liver disease | <gastroenterology> Alcoholic cirrhosis is a condition of irreversible liver disease due to the chronic inflammatory and toxic effects of ethanol on the liver. In cirrhosis, the liver cells are replaced by fibrous scar tissue. Fibrosis leads to the development of portal hypertension. The development of cirrhosis is directly related to the duration and quantity of alcohol consumption. The manifestations of cirrhosis are related to the liver's inability to not adequately remove waste products from the bloodstream and the effects of portal hypertension. (15 Nov 1997) |
| anterior part of diaphragmatic surface of liver | The part of the diaphragmatic surface of the liver deep to the costal arches and the xiphoid process. Synonym: pars anterior faciei diaphragmatis hepatis. (05 Mar 2000) |
| bare area of liver | The area on the posterior surface of the liver which is fused with the diaphragm and therefore not covered by peritoneum. Synonym: area nuda hepatis. (05 Mar 2000) |
| benign liver tumours | <radiology> EPITHELIAL TUMORS, nodular transformation, focal nodular hyperplasia, hepatocellular adenoma, MESENCHYMAL TUMORS, lipoma, myelolipoma, angiomyolipoma, leiomyoma, infantile haemangioendothelioma, haemangioma, benign mesothelioma, MIXED TISSUE TUMORS, mesenchymal hamartoma, benign teratoma, MISCELLANEOUS, adrenal rest tumours, pancreatic rest (12 Dec 1998) |
| calcified liver metastases | <radiology> Mucinous carcinoma of GI tract (colon, rectum, stomach), endocrine pancreatic carcinoma, leiomyosarcoma, osteosarcoma, malignant melanoma, papillary serous ovarian cystadenocarcinoma, lymphoma, pleural mesothelioma, neuroblastoma, breast carcinoma, medullary thyroid carcinoma, renal cell carcinoma, lung carcinoma, testicular carcinoma see: liver metastases (12 Dec 1998) |