| Mabs | monoclonal antibodies |
|---|---|
| MAS | magic angle spinning; Manifest Anxiety Scale; maximum average score; McCune-Albright syndrome; mecon... |
| MCG | magnetocardiogram; membrane coating granule; monoclonal gammopathy |
| MG | Marcus Gunn [pupil]; margin; medial gastrocnemius [muscle]; membranous glomerulonephritis; menopausa... |
| MGUS | monoclonal gammopathies of undetermined significance |
| catalytic antibody | <chemistry> Antibody raised against a transition state analogue (e.g. A phosphate analogue of a carboxylic acid ester transition state) that can then catalyse the analogous chemical reaction, though not as effectively as a true enzyme. (16 Mar 1998) |
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| Vi antibody | A form of antibody that agglutinates highly virulent strains of Salmonella typhi, i.e., cells with Vi antigen; such bacteria are not agglutinable with O antiserum until the Vi antigen is destroyed. See: Vi antigen. (05 Mar 2000) |
| cell-bound antibody | A term used for antibody on the surface of cells that may be bound either through antigen combining sites or other sites such as the Fc region. (05 Mar 2000) |
| CF antibody | Antibody that combines with and sensitises antigen leading to the activation of complement, which may result in cell lysis. Synonym: CF antibody, sensitizing substance. (05 Mar 2000) |
| chimeric antibody | <immunology> An antibody that contains polypeptides from different species. (05 Jan 1998) |
| chimeric/humanised antibody | <immunology> Genetically engineered combination of a human and mouse antibody. Because a monoclonal antibody is always made with mice cells, it causes an immune response when injected into humans. By replacing the constant regions of a mouse antibody with those of a human antibody, an antibody that binds to an antigen like the original monoclonal antibody, but which is recognised by the human immune system like a human protein, can be manufactured. Alternatively, only those amino acids directly involved in antigen binding are transferred from the mouse antibody into the framework of the human antibody, with a similar result. (05 Jan 1998) |
| microsomal antibody | This special serologic test is used to measure thyroid anti-microsomal antibody in the bloodstream. This test can be performed from a simple venipuncture specimen. The anti-microsomal antibody or microsomal antibody test is used to diagnose conditions such as Hashimoto's thyroiditis and other autoimmune disorders. (27 Sep 1997) |
| warm antibody | <haematology, immunology> most IgG antibodies react better at 37쵣 than at lower temperatures, especially against red cell antigens. These are the warm antibodies as contrasted with cold agglutinins, especially IgM, that agglutinate below 28쵣. (18 Nov 1997) |
| Wassermann antibody | Antibody, evoked during syphilitic infections, that combines with cardiolipin in the presence of lecithin and cholesterol; it is distinct from the treponema-immobilizing antibody. (05 Mar 2000) |
| cold antibody | See: cold agglutinin. (05 Mar 2000) |
| cold-reactive antibody | See: cold agglutinin. (05 Mar 2000) |
| complement-fixing antibody | Antibody that combines with and sensitises antigen leading to the activation of complement, which may result in cell lysis. Synonym: CF antibody, sensitizing substance. (05 Mar 2000) |
| complete antibody | An antibody which causes agglutination of erythrocytes when they are suspended either in saline or in a protein medium. (05 Mar 2000) |
| polyclonal antibody | An antibody produced by several clones of B lymphocytes as would be the case in a whole animal. Usually refers to antibodies raised in immunised animals, whereas a monoclonal antibody is the product of a single clone of B lymphocytes, usually maintained in vitro. (18 Nov 1997) |
| cross-reacting antibody | <immunology> Antibody specific for group antigens, i.e., those with identical functional groups, antibody for antigens that have functional groups of closely similar, but not identical, chemical structure. (05 Mar 2000) |
| monoclonal antibody |
An antibody that recognizes one specific sequence of amino acids.
출처: urology.ucsf.edu/patientGuides/termsM.html
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| monoclonal antibody |
A pure antibody that recognizes only one epitope. It is isolated from a single B-cell and grown in cell culture.
출처: www.aidsinfonyc.org/hivplus/issue9/report/glossary...
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| monoclonal antibody |
are pure antibodies designed to bind to a specific antigen target.
출처: www.chemi-tek.com/dic_lista.asp
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| monoclonal antibody |
An antibody that is made in large amounts in a laboratory and may be used to treat certain diseases.
출처: www.beyondpsoriasis.com/glossary.jsp
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| monoclonal antibody therapy |
The use of monoclonal antibodies to suppress immune function, kill target cells, or treat specific inflammatory diseases. Because of their high level of specificity, they bind to precise cellular or molecular targets.
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