| ABS | abdominal surgery; acute brain syndrome; Adaptive Behavior Scale; admitting blood sugar; adult bovin... |
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| ARGS | antitrypsin-related gene sequence |
| ARS | acquiescence response scale; adult Reye's syndrome; alcohol-related seizures; alizarin red S; Americ... |
| CMGS | chopped meat-glucose-starch [medium]; Clinical Molecular Genetics Society |
| CPMG | Carr-Purcell-Meiboom-Gill [sequence] |
| molecular weight ratio | The sum of the atomic weight's of all the atoms constituting a molecule; the mass of a molecule relative to the mass of a standard atom, now 12C (taken as 12.000). Relative molecular mass (Mr) is the mass relative to the dalton and has no units. See: atomic weight. Synonym: molecular mass, molecular weight ratio, relative molecular mass. (05 Mar 2000) |
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| heparin, low-molecular-weight | <chemical> Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of haemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism. Pharmacological action: anticoagulant, fibrinolytic agent. (12 Dec 1998) |
| directed molecular evolution | Techniques used to produce molecules exhibiting properties that conform to the demands of the experimenter. (12 Dec 1998) |
| epidemiology, molecular | The application of molecular biology to the answering of epidemiological questions. The examination of patterns of changes in DNA to implicate particular carcinogens and the use of molecular markers to predict which individuals are at highest risk for a disease are common examples. (12 Dec 1998) |
| european molecular biology lab gene bank | <molecular biology> A large database of DNA sequence data in Heidelberg, Germany, compiled from international sources. It is the European equivalent to the Genbank DNA sequence databank in the United States of America. WWW: EMbase. (09 Oct 1997) |
| evolution, molecular | Evolution at the molecular level of DNA sequences and proteins. (rieger et al., glossary of genetics: classical and molecular, 5th ed) (12 Dec 1998) |
| kinetic molecular theory | <chemistry> This theory assumes that molecules must collide in order to react. The more collisions the more likely it is for a reaction to occur. However, depending on the conditions, only a small fraction of the collisions are effective in producing a reaction. There are several constraints. In order for a reaction to occur, bonds initially are broken, which requires energy. This energy depends on the type of the reaction and comes from the kinetic energies that the molecules possess before the collision. It is called the activation energy. Increasing the temperature increases the kinetic energies and more collisions will occur. In adition, at a higher temperature a greater number of the reacting molecules might possess an energy equal to or greater than the activation energy. However the molecules must also collide in a specific orientation, called the steric factor in order for a reaction to occur. A reaction will only be successful, if the collision has enough energy to be either equal to or greater than the activation energy and if the orientation of the collision allows for correct bond formation. These factors are in the Arrhenius equation: k = zp The rate constant k is proportional to the Arrhenius factor A. A is the product of the collision frequency z, and the steric factor p. The fraction of collisions with sufficient energy to produce a reaction are in the term of the equation. (09 Jan 1998) |
| kininogen, high-molecular-weight | A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with prekallikrein. Hmwk is split by plasma kallikrein to produce bradykinin. The complex is a cofactor in the activation of coagulation factor xii. The product of this reaction, xiia, in turn activates prekallikrein to kallikrein. (12 Dec 1998) |
| kininogen, low-molecular-weight | A protein, molecular weight 50 kD, located in various normal tissues. Upon cleavage by kallikrein or other kallikreins, it forms kallidin. Kallidin, in turn, is converted into bradykinin. (12 Dec 1998) |
| alu sequence | Any of a family of short (300 basepairs long) repeated sequences that occur throughout the human genome. (09 Oct 1997) |
| amino acid sequence | The sequence of amino acids as arrayed in chains, sheets, etc., within the protein molecule. This is referred to as the primary structure of proteins. It is of fundamental importance in determining protein conformation. (12 Dec 1998) |
| autonomously replicating sequence | <molecular biology> This is a chromosomal sequence that allows plasmids to replicate on their own in yeast. (02 Jan 1998) |
| base sequence | <molecular biology> The order of nucleotide bases in a DNA molecule. (09 Oct 1997) |
| base sequence analysis | <molecular biology> A method, sometimes automated, for determining the base sequence. (09 Oct 1997) |
| canonical sequence | Of a series of related DNA, RNA or protein sequences, the sequence that reflects the most common choice of base or amino acid at each position. Areas of particularly good agreement often represent conserved functional domains. The generation of consensus sequences has been subjected to intensive mathematical analysis. (18 Nov 1997) |