| diabetes insipidus | <disease, endocrinology> Rare form of diabetes in which the kidney tubules do not reabsorb sufficient water. This can be because (a) either the renal tubules have defective receptors for antidiuretic hormone (ADH, vasopressin) or (b) a class of aquaporin water channel in the collecting duct is defective or (c) there is inadequate ADH production by the pituitary, leading to the excessive production of dilute urine. (18 Nov 1997) |
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| diabetes insipidus, nephrogenic | A rare congenital and familial form of diabetes insipidus, resulting from failure of the renal tubules to absorb water. There is excessive production of antidiuretic hormones but the tubules fail to respond to it. (12 Dec 1998) |
| diabetes intermittens | Diabetes mellitus in which there are periods of relatively normal carbohydrate metabolism followed by relapses to the previous diabetic state. (05 Mar 2000) |
| diabetes related peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
| diabetes, type 1 | Insulin dependent diabetes or juvenile diabetes. (12 Dec 1998) |
| diabetes, type 2 | Non-insulin dependent diabetes, adult-onset diabetes or insulin-resistant diabetes. (12 Dec 1998) |
| insulin dependent diabetes | A form of diabetes that requires the daily injection of the hormone insulin to maintain normal body chemistry. Avoidance of insulin in these patients will result in a severe metabolic derangement known as diabetic ketoacidosis. (27 Sep 1997) |
| insulinopenic diabetes | Any form of diabetes mellitus resulting from inadequate secretion of insulin. (05 Mar 2000) |
| thiazide diabetes | Impaired carbohydrate metabolism associated with the use of thiazide diuretic drugs; severe manifestations are seen in persons having diabetes mellitus, but impairment is mild or absent in nondiabetic individuals. (05 Mar 2000) |
| type 1 diabetes | <endocrinology> Also referred to as juvenile onset diabetes. Underlying cause is likely genetic. Usually treated with daily insulin dosing. Insulin is necessary for the body to properly utilise glucose. Without insulin, glucose accumulates in the bloodstream. (27 Sep 1997) |
| type 2 diabetes | <endocrinology> Also referred to as adult-onset diabetes. More common in the middle-age, overweight individual. Usually treated by diet control, weight reduction or oral hypoglycemic agents. (27 Sep 1997) |
| type I diabetes | A chronic condition in which the pancreas makes little or no insulin because the beta cells have been destroyed. The body is then not able to use the glucose (blood sugar) for energy. IDDM usually comes on abruptly, although the damage to the beta cells may begin much earlier. The signs of IDDM are a great thirst, hunger, a need to urinate often, and loss of weight. To treat the disease, the person must inject insulin, follow a diet plan, exercise daily, and test blood glucose several times a day. IDDM usually occurs in children and adults who are under age 30. This type of diabetes used to be known as juvenile diabetes, juvenile-onset diabetes, and ketosis-prone diabetes. (09 Oct 1997) |
| type II diabetes | <disease> An often mild form of diabetes mellitus of gradual onset, usually in obese individuals over age 35; absolute plasma insulin levels are normal to high, but relatively low in relation to plasma glucose levels; ketoacidosis is rare, but hyperosmolar coma can occur; responds well to dietary regulation and/or oral hypoglycaemic agents, but diabetic complications and degenerative changes can develop. (05 Mar 2000) |
| juvenile diabetes | <endocrinology> A severe metabolic disorder which has an abrupt onset before the age of twenty. In it, an insulin deficiency prevents the body from using carbohydrates properly and forces it to rely mainly on protein metabolism. Treatment of the disease includes strict dietary regulation and mandatory insulin injections. (09 Oct 1997) |
| juvenile onset diabetes | A form of diabetes which has its onset in childhood. Also referred to as type I diabetes, juvenile onset diabetes or insulin-dependent diabetes. The exact cause is unknown but genetic factors seem to play a major role. Symptoms include excessive thirst, increased urination, weight loss (despite increased appetite), nausea, vomiting, fatigue and absent menstruation. Treatment includes education and regular insulin therapy. See: insulin-dependent diabetes mellitus (22 Sep 2002) |