| MPP | massive peritoneal proliferation; methyl phenylpyridinium; medical personnel pool; mercaptopyrazide ... |
|---|---|
| PAG | periaqueductal gray [matter]; polyacrylamide gel; pregnancy-associated globulin; proliferation-assoc... |
| PAGA | proliferation-associated gene A |
| PIF | paratoid isoelectric focusing variant protein; peak inspiratory flow; proinsulin-free; prolactin-inh... |
| SP | sacroposterior; sacrum to pubis; salivary progesterone; schizotypal personality; semi-private [room]... |
| lymphocyte count | A count of the number of lymphocytes in the blood. (12 Dec 1998) |
|---|---|
| lymphocyte depletion | Immunosuppression by reduction of circulating lymphocytes or by T-cell depletion of bone marrow. The former may be accomplished in vivo by thoracic duct drainage or administration of antilymphocyte serum. The latter is performed ex vivo on bone marrow before its transplantation. (12 Dec 1998) |
| lymphocyte function associated antigen | A member of the integrin family that is expressed on all leukocytes and binds to ICAM-1 and ICAM-2 on a variety of cells. (05 Mar 2000) |
| lymphocyte function-associated antigen-1 | A heterodimer molecule widely expressed on cells of haematopoietic origin. Cd11a antigen comprises the alpha chain and the CD18 antigen (antigens, CD18) the beta chain. Lfa-1 is a major receptor of T-cells, B-cells, and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 (icam-1) has been defined as a ligand for lfa-1. (12 Dec 1998) |
| lymphocyte-oriented kinase | <enzyme> An ste20-like protein kinase; genbank d89728 Registry number: EC 2.7.10.- Synonym: lok gene product (26 Jun 1999) |
| lymphocyte specific protein tyrosine kinase p56(lck) | <enzyme> This enzyme is a lymphoid specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the il-2 receptor, and is thought to be involved in the earliest steps of tcr-mediated T-cell activation. Registry number: EC 2.7.11.- (12 Dec 1998) |
| lymphocyte subsets | A classification of lymphocytes based on structurally or functionally different populations of cells. (12 Dec 1998) |
| lymphocyte transformation | <haematology> The change in morphology and behaviour of lymphocytes exposed to a mitogen or to an antigen to which they have been primed. The result is the production of lymphoblasts, cells that are actively engaged in protein synthesis and that divide to form effector populations. Should not be confused with transformation of the type associated with oncogenic viruses and activation is therefore perhaps a better term. (18 Nov 1997) |
| lymphocyte transfusion | The transfer of lymphocytes from a donor to a recipient or reinfusion to the donor. (12 Dec 1998) |
| acetyl reduction assay | <investigation> A technique for measuring the nitrogen fixation activity in photosynthetic organisms. It uses a flame ionisation detector and a gas chromatography apparatus to determine the reduction of acetylene to ethylene by the enzyme nitrogenase. (06 May 1997) |
| Ames assay | <procedure> One of a number of procedures used to test substances for likely ability to cause cancer that combines the use of animal tissue to generate active metabolites of the substance with a test for mutagenicity in bacteria. (18 Nov 1997) |
| antibiotic assay | <investigation> A test to determine how sensitive a bacterial or fungal strain is to arange of antibiotics bymeasuring the microbes' ability to grow in astandard dilution of each chemical. (09 Oct 1997) |
| assay | <procedure> The determination of the amount of a particular constituent of a mixture or of the biological or pharmacological potency of a drug. (10 May 1997) |
| bandshift assay | <investigation> An assay for proteins, such as transcription factors, that bind specific DNA sequences. A labelled oligonucleotide corresponding to the recognition sequence is incubated with an appropriate nuclear protein extract and run on a nondenaturing acrylamide gel. Oligonucleotides that have been bound by proteins are retarded relative to those that are unbound. (18 Nov 1997) |
| biological assay | <technique> Once a pharmaceutical protein is isolated from the cells in which it was grown, researchers perform tests to measure the protein's biological activity. It must maintain a certain minimal level of biological activity to be used for animal or clinical testing or, later, for market. Researchers also test to confirm that the isolated protein is identical to the desired protein. (21 Mar 1998) |