leuko : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 4

Leukodystrophy, Globoid Cell - 새창 An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.
Synonyms : Classic Globoid Cell Leukodystrophy, Early-Onset Globoid Cell Leukodystrophy, Galactosylceramide-beta-Galactosidase Deficiency Disease, Globoid Body Sclerosis, Diffuse, Globoid Cell Leukodystrophy, Globoid Leukodystrophy, Krabbe Leukodystrophy
Leukodystrophy, Metachromatic - 새창 An autosomal recessive metabolic disease caused by a deficiency of arylsulfatase A (CEREBROSIDE-SULFATASE) leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.
Synonyms : Greenfield Disease, Greenfield's Disease, Leukodystrophy, Metachromatic, Adult, Leukodystrophy, Metachromatic, Juvenile, Metachromatic Leukodystrophy, Adult-Type, Metachromatic Leukodystrophy, Infant, Metachromatic Leukodystrophy, Infant-Type
Leukoedema, Oral - 새창 A disorder of the buccal mucosa resembling early leukoplakia, characterized by the presence of filmy opalescence of the mucosa in the early stages to a whitish gray cast with a coarsely wrinkled surface in the later stages, associated with intracellular edema of the spinous or malpighian layer. (Dorland, 27th ed)
Synonyms : Leukoedemas, Oral, Oral Leukoedema, Oral Leukoedemas
Leukoencephalitis, Acute Hemorrhagic - 새창 A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)
Synonyms : Encephalomyelitis, Acute Necrotizing Hemorrhagic, Encephalomyelitis, Hemorrhagic Necrotizing, Encephalomyelitis, Necrotizing Hemorrhagic, Hemorrhagic Encephalomyelitis, Necrotizing, Hemorrhagic Necrotizing Encephalomyelitis, Hurst Syndrome, Hurst's Disease
Leukoencephalopathy, Progressive Multifocal - 새창 An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
Synonyms : JC Polyomavirus Encephalopathy, Encephalopathies, JC Polyomavirus, Encephalopathy, JC Polyomavirus, JC Polyomavirus Encephalitis, Leukoencephalopathies, Progressive Multifocal, Multifocal Leukoencephalopathies, Progressive