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leukoagglutinin An antibody that agglutinates white blood cells.
(05 Mar 2000)
leukobilin Synonym: white bile.
Origin: Leuko-+ L. Bilis, bile
(05 Mar 2000)
leukoblast An immature white blood cell that is transitional between the lymphoidocyte (or the myeloblast of Naegeli and Downey) and the promyelocyte; the cytoplasm is polychromatophilic or slightly acidophilic and, as compared with the lymphoidocyte, the nuclear network of chromatin is thicker and the nucleoli less distinct.
Synonym: proleukocyte.
Origin: Leuko-+ G. Blastos, germ
(05 Mar 2000)
leukoblastosis A general term for the abnormal proliferation of leukocytes, especially that occurring in myelocytic and lymphocytic leukaemia.
(05 Mar 2000)
leukochloroma <tumour> Synonym: myelocytomatosis.
Origin: Leuko-+ G. Chloros, green, + -oma, tumour
(05 Mar 2000)
leukocidin A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci and manifests a destructive action on leukocytes, with or without lysis of the cells.
Origin: Leukocyte + L. Caedo, to kill
(05 Mar 2000)
leukocidins Substances that are toxic to leukocytes. Specifically exotoxins produced by some pathogenic staphylococci and streptococci that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
(12 Dec 1998)
leukocoria Reflection from a white mass within the eye giving the appearance of a white pupil.
Synonym: leukokoria, white pupillary reflex.
Origin: Leuko-white, + G. Kore, pupil
(05 Mar 2000)
leukocytactic Pertaining to, characterised by, or causing leukocytotaxia.
Synonym: leukocytactic, leukotactic.
(05 Mar 2000)
leukocytal Pertaining to or characterised by leukocytes.
Synonym: leukocytal.
(05 Mar 2000)
leukocytaxia 1. The active ameboid movement of leukocytes, especially the neutrophilic granulocytes, either toward (positive leukocytotaxia) or away from (negative leukocytotaxia) certain microorganisms as well as various substances frequently formed in inflamed tissue.
2. The property of attracting or repelling leukocytes.
Synonym: leukocytaxia, leukocytaxis, leukotaxia, leukotaxis.
Origin: Leukocyte + G. Taxis, arrangement
(05 Mar 2000)
leukocyte <haematology> White corpuscles in the blood. They are spherical, colourless and nucleated masses involved with host defenses.
Normal white blood cell counts are variable with age and sex. Normal adult range is 4, 500 to 11,000 cells per cubic millimetre of blood. Slightly higher counts are seen in children. Elevated counts can be seen in cases of inflammation and infection.
See: leucocytes, basophils, coelomocytes, eosinophils, haemocytes, lymphocytes, neutrophils, monocytes.
Acronym: WBC
(13 Nov 1997)
leukocyte adherence assay test A test to detect the ability of leukocytes to adhere to bacteria, performed in vitro using nylon fibres to measure adherence.
(05 Mar 2000)
leukocyte adherence inhibition test Test for cell-mediated antitumour immunity and related serum blocking factors based on the finding that leukocytes from cancer patients, but not from controls, when mixed in vitro with antigenic extracts of tumours of the same histological type, undergo a diminution in their normal adherence to glass surfaces. Sera from tumour-bearing patients block the lai reaction of their own leukocytes or those of other patients with the same type of tumour.
(12 Dec 1998)
leukocyte adhesion deficiency An inherited disorder (autosomal recessive) in which there is a defective CD18 adherence complex that disturbs leukocyte chemotaxis. It is characterised by recurrent bacterial infections and impaired wound healing.
(05 Mar 2000)
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