| pulse chase | <biochemistry> An experimental protocol used to determine cellular pathways, such as precursor product relationships. A sample organism, cell or cellular organelle), is exposed for a relatively brief time to a radioactively labelled molecule, the pulse. It is then replaced with an excess of the unlabelled molecule, the chase (cold chase). The sample is then examined at various later times to determine the fate of radioactivity incorporated during the pulse. (15 Dec 1997) |
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| pulse-chase experiment | An experiment in which an enzyme, a metabolic pathway, a culture of cells, etc., interacts with a brief addition (pulse) of a labelled compound followed by its removal and replacement (chase) by an excess of unlabelled compound. (05 Mar 2000) |
| pulse curve | <physiology> A tracing, called a pulse tracing, consisting of a series of curves corresponding with the beats of the heart, obtained by the application of the sphygmograph. Origin: Gr. Pulse + -gram. Source: Websters Dictionary (01 Mar 1998) |
| pulse deficit | The absence of palpable pulse waves in a peripheral artery for one or more heart beats, as is often seen in atrial fibrillation, the number of such missing pulse waves (usually expressed as heart rate minus pulse rate per minute). (05 Mar 2000) |
| pulse duration | The interval between onset of the leading edge and the end of the trailing edge of a pulse wave. (05 Mar 2000) |
| pulse field electrophoresis | <investigation> A method used for high resolution electrophoretic separation of very large (megabase) fragments of DNA. Electric fields 100 |
| pulse-field gel electrophoresis | Gel electrophoresis in which, after electrophoretic migration has begun, the current is briefly stopped and reapplied in a different orientation; allows for the purification of long DNA molecules. Synonym: pulsed-field gel electrophoresis. (05 Mar 2000) |
| pulse generator | A device that produces an electrical discharge with a regular or rhythmic wave form in which the electromotive force varies in a specific pattern in relation to time; e.g., in an electronic pacemaker, it produces an electric discharge at regular intervals, and these intervals may be modified by a sensory circuit which can reset the time-base for subsequent discharge on the basis of other electrical activity, such as that produced by spontaneous cardiac beating. (05 Mar 2000) |
| pulse granuloma | <pathology> An inflammatory infiltrate containing foreign body giant cells and eosinophilic material. Fragments of foreign material resembling vegetable matter may be included. Synonym: pulse granuloma. (05 Mar 2000) |
| pulse height analyzer | Electronic circuitry that determines the energy of scintillations recorded by a detector, allowing use of a discriminator to select for photons of a specific type. (05 Mar 2000) |
| pulse period | The reciprocal of the repetition rate; e.g., the interval between leading edges of successive pulses. (05 Mar 2000) |
| pulse pressure | The variation in blood pressure occurring in an artery during the cardiac cycle; it is the difference between the systolic or maximum and diastolic or minimum pressure's. (05 Mar 2000) |
| pulse radiolysis | Use of a pulse of X-rays or fast electrons to generate free radicals for spectroscopic examination. (12 Dec 1998) |
| pulse rate | Rate of the pulse as observed in an artery; recorded as beats per minute. (05 Mar 2000) |
| pulse therapy | A short, intensive course of pharmacotherapy, usually given at intervals such as weekly or monthly; often used in chemotherapy of malignancy. (05 Mar 2000) |