| CH50 | Hemolytic Complement 50; ¿ëÇ÷ º¸Ã¼ °Ë»ç¹ý; (30)50 - (40)(66)80 Unit/mL |
|---|---|
| Gc globulin | Group-specific complement globulin |
| AC | abdominal circumference; abdominal compression; absorption coefficient; abuse case; acetate; acetylc... |
| AICF | autoimmune complement fixation |
| ASAC | acidified serum-acidified complement |
| complement pathway, alternative | The complement activation sequence initiated by the activation of complement factor c3, which is triggered by the interaction of microbial polysaccharides and properdin without participation of an antigen-antibody reaction. (12 Dec 1998) |
|---|---|
| complement pathway, classical | The sequential activation of complement, initiated by antigen-antibody complex and the binding of complement factor c1q to the fc region of the antibody. (12 Dec 1998) |
| complement system | A group of more than 20 serum proteins, some of which can be serially activated and participate in a cascade resulting in cell lysis. (05 Mar 2000) |
| complement unit | The smallest amount (highest dilution) of complement that will cause haemolysis of a unit of red blood cells in the presence of a haemolysin unit. Synonym: alexin unit. (05 Mar 2000) |
| component of complement | Any one of the nine distinct protein units (designated C1 through C9 and distributed in the a, b, and g electrophoretic partitions of normal serum) that effect the immunological activities long associated with complement. C1 is a complex of three subunits: C1q, C1r, and C1s. C1q (overbar indicates "active form") activates proenzyme C1r to C1r which activates C1s to C1s (also known as C1 esterase), which converts proenzyme C2 to C2b and produces C4b from C4. C2b combines with C4b to form "classical-complement-pathway C3/C5 convertase" (also known as C3 convertase, C5 convertase, and C42). This enzyme cleaves C3 to C3a and C3b, and C5 to yield C5a and C5b, as does "alternative-complement-pathway C3/C5 convertase" (also known as proenzyme factor B, properdin factor B, C3 proactivator, and heat-labile factor). Complement factor I (also known as C3b or C3b/C4b inactivator) inactivates C3b and C4b by a different proteolytic cleavage. Several autosomal recessive disorders have been identified in which one or more of the complement components have been deficient or completely absent. (05 Mar 2000) |
| heparin complement | The protein component of heparin in blood. (05 Mar 2000) |
| thyrotoxic complement-fixation factor | A form of thyrotoxin; an antigen found most readily in thyroid tissue from thyrotoxic individuals; known to be chemically and immunologically distinct from thyroglobulin, and fixes complement when combined with antibody related to the gamma-globulin fraction of serum. With the exception of extremely small concentrations, the antigen is rarely found in normal glands or in diseased glands that are not associated with thyrotoxicosis; it is probably an intracellular substance (possibly a constituent of the "microsomal fraction"), and does not contain iodine in significant quantity. Not related to the complement-fixation reaction occurring with serum in Hashimoto's disease, in which the antigen is thyroglobulin. (05 Mar 2000) |
| genetic | <biology> Pertaining to reproduction or to birth or origin. (07 May 1998) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| genetic assimilation | <genetics> A situation in which a characteristic that is normally expressed only in certain environmental situations becomes fixed in a population so that it no longer requires environmental factors to be expressed. (07 May 1998) |
| genetic association | The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic. (05 Mar 2000) |
| genetic block | <biochemistry, molecular biology> An obstruction in a biochemical pathway caused by a mutation that has crippled production of an enzyme critical to the pathway. (07 May 1998) |
| genetic burden | The genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct and depending on the details of inheritance and phenotype must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.) (05 Mar 2000) |
| genetic carrier | An unaffected heterozygote bearing a usually harmful recessive gene, a cancer that bears a dominant but latent age-dependent trait to have offspring with unbalanced karyotypes. (05 Mar 2000) |
| genetic code | <molecular biology> Relationship between the sequence of bases in nucleic acid and the order of amino acids in the polypeptide synthesised from it. A sequence of three nucleic acid bases (a triplet) acts as a codeword (codon) for one amino acid. (18 Nov 1997) |
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