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ACGPOMS American College of General Practitioners in Osteopathic Medicine and Surgery
AGCT antiglobulin consumption test; Army General Classification Test
AGED automated general experimental device
ASG advanced cell group; American Society for Genetics; Army Surgeon General; aspermiogenesis
DGIM Division of General Internal Medicine
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GLM General Linear Model
GMC General Medical Council
GP general medical practitioner
GMS General Medical Service
GM general movement
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habit chorea <clinical sign> An involuntary compulsive, repetitive, stereotyped movement, resembling a purposeful movement because it is coordinated and involves muscles in their normal synergistic relationships, tics usually involve the face and shoulders.
(18 Nov 1997)
posthemiplegic chorea A unilateral athetosis involving hemiplegic limbs, usually seen in children.
Synonym: posthemiplegic chorea.
(05 Mar 2000)
saltatory chorea Rhythmic dancing movements, as in procursive chorea.
(05 Mar 2000)
procursive chorea A form in which the patient whirls around, runs forward, or exercises a sort of rhythmic dancing movement.
Synonym: dancing chorea.
(05 Mar 2000)
hemilateral chorea Chorea involving the muscles on one side only.
Synonym: chorea dimidiata, hemilateral chorea.
(05 Mar 2000)
Henoch's chorea A disorder in which sudden spasmodic coordinated movements of certain muscles or groups of physiologically related muscles occur at irregular intervals.
Synonym: Henoch's chorea.
(05 Mar 2000)
hereditary chorea A progressive disorder usually beginning in young to middle age, consisting of a triad of choreoathetosis, dementia, and autosomal dominant inheritance with complete penetrance. Bilateral marked wasting of the putamen and the head of the caudate nucleus is characteristic.
Synonym: chronic progressive chorea, degenerative chorea, hereditary chorea, Huntington's disease.
(05 Mar 2000)
senile chorea A disorder resembling Sydenham's chorea, not associated with cardiac disease or dementia, occurring in the aged.
(05 Mar 2000)
hospitals, general Large hospitals with a resident medical staff which provides continuous care to maternity, surgical and medical patients.
(12 Dec 1998)
Huntington chorea <neurology> An inherited adult-onset disease of the central nervous system.
It is characterised by dementia and bizarre involuntary movements. The disease is progressive and there is currently no known cure.
The identification of the gene (huntingtin) on chromosome 4p now allows for direct mutation analysis. The gene contains a trinucleotide repeat (CAG) that is found to be expanded in length in affected patients. The normal allele size ranges from 11 to 34 triplet repeat units, while 42 repeats or greater is considered diagnostic of Huntington disease.
As in other trinucleotide repeat disorders, the phenomenom of anticipation has been observed, in this case expressed as earlier age of onset in offspring, particularly with paternal transmission. A further complication is the presence of two neighboring trinucleotide repeats (both CCG) which can expand independently without causing the disease.
Early PCR primer sets encompassed these adjacent repeats, potentially yielding false positive test results, newer primers hone in more closely on the CAG repeat sequence.
Careful attention must be paid to the psychosocial support structure of prospective test subjects in Huntington disease genetic counseling. Established protocols require systematic neuropsychiatric assessment and informed consent prior to DNA testing.
Inheritance: autosomal dominant.
(29 Dec 1997)
Huntington's chorea A progressive disorder usually beginning in young to middle age, consisting of a triad of choreoathetosis, dementia, and autosomal dominant inheritance with complete penetrance. Bilateral marked wasting of the putamen and the head of the caudate nucleus is characteristic.
Synonym: chronic progressive chorea, degenerative chorea, hereditary chorea, Huntington's disease.
(05 Mar 2000)
hysterical chorea Conversion hysteria in which involuntary, quick, and purposeless (choreiform) movements constitute the chief feature.
(05 Mar 2000)
dancing chorea A form in which the patient whirls around, runs forward, or exercises a sort of rhythmic dancing movement.
Synonym: dancing chorea.
(05 Mar 2000)
degenerative chorea A progressive disorder usually beginning in young to middle age, consisting of a triad of choreoathetosis, dementia, and autosomal dominant inheritance with complete penetrance. Bilateral marked wasting of the putamen and the head of the caudate nucleus is characteristic.
Synonym: chronic progressive chorea, degenerative chorea, hereditary chorea, Huntington's disease.
(05 Mar 2000)
surgeon general The chief medical officer in the U.S. Army, Navy, Air Force, or Public Health Service. In some foreign military services any member of the medical corps who has the rank of general, not necessarily the chief medical officer.
(05 Mar 2000)
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