| malignant tumour | A mass of cancer cells. These cells have uncontrolled growth and will invade surrounding tissues and spread to distant sites of the body, setting up new cancer sites, a process called metastasis. (09 Oct 1997) |
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| papillary tumour | A tumour shaped like a small mushroom with its stem attached to the inner lining of the bladder. (12 Dec 1998) |
| mammary tumour virus | <organism, virology> Retrovirus that induces mammary carcinoma in mice. Isolated from highly inbred strains that had very high incidence of the tumours, after the discovery that the disease was transmitted by nursing mothers in milk. Endogenous provirus present in germ line of all inbred mice. Transcription of the provirus is regulated by a viral promoter that increases transcription in response to glucocorticoid hormones. May transform by proviral insertion activating the cellular int 1 oncogene (18 Nov 1997) |
| mammary tumour viruses, mouse | The type species of mammalian type b retroviruses (retroviruses type b, mammalian) commonly latent in mice. It causes mammary adenocarcinoma when in a genetically susceptible strain of mice and when the appropriate hormonal influences operate. (12 Dec 1998) |
| mammary tumour virus of mice | Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences. Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus. (05 Mar 2000) |
| ranine tumour | <medicine> A cyst formed under the tongue by obstruction of the duct of the submaxillary gland. Origin: L, a little frog, a little swelling on the tongue of cattle, dim. Of rana a frog. Source: Websters Dictionary (01 Mar 1998) |
| paraffin tumour | A tumefaction, usually a granuloma, caused by the prosthetic or therapeutic injection of paraffin into the tissues; sometimes used with reference to similar lesions resulting from the injection of any oil, wax, or the like. See: lipogranuloma. Synonym: paraffin tumour. (05 Mar 2000) |
| Rathke's pouch tumour | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |
| genes, wilms' tumour | Tumour suppressor genes located in the 11p13 region on the short arm of human chromosome 11. The absence of these genes is associated with the formation of wilms' tumour. (12 Dec 1998) |
| receptors, tumour necrosis factor | Cell surface receptors that bind tumour necrosis factor and trigger changes which influence the behaviour of cells. The two recognised tumour necrosis factor receptors are designated alpha and beta receptors. Both receptors bind both alpha and beta tumour necrosis factors with high affinity, and both are members of the nerve growth factor receptor family. (12 Dec 1998) |
| Recklinghausen's tumour | A small, circumscribed, benign tumour of the genital tract, composed of small glandlike spaces lined by flattened or cuboidal mesothelium-like cells. (12 Dec 1998) |
| carotid body tumour | An invariably benign, encapsulated, firm round mass at the bifurcation of the common carotid artery, with nests of large polyhedral cells in alveolar or organoid arrangement. It is usually asymptomatic but large masses may encroach upon the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies. (12 Dec 1998) |
| germ cell tumour | A type of brain tumour. (12 Dec 1998) |
| giant cell tumour | <radiology> Osteoclastoma, GCT, any age, typically 20-35, site: metaphysis into epiphysis, 50% at knee (distal femur, proximal tibia), long bones, patella, spine, eccentric, expansile, with or without soap bubble appearance, treatment: curette, fill with methacrylate, 10% recur, a few are premalignant or malignant, cannot determine malignancy by XR (12 Dec 1998) |